Silostan CR Tablets 200 Milligrams (Silostazol)

Adult dose

For silostazol, the usual adult dose is 200 mg orally once a day. This medicine should be taken on an empty stomach, avoiding meals.

This medicine may increase heart rate, which could lead to possible angina symptoms; therefore, careful observation for symptoms such as chest pain is required. Patients with bleeding or at high risk of bleeding, patients with congestive heart failure, patients allergic to this medicine, and women who are pregnant or breastfeeding should not use this medicine. Patients taking anticoagulants or antiplatelet agents, menstruating women, patients with heart disease, patients with severe kidney or liver dysfunction, and diabetic patients should use this medicine cautiously. This medicine may cause side effects such as headache, dizziness, dyspepsia, vomiting, myalgia, flushing of the face, and more severe adverse reactions including bleeding, blood abnormalities, interstitial pneumonia, and heart issues; hence, if any abnormal symptoms occur, immediate consultation with a healthcare professional is necessary. This medicine should be given to patients with cerebral infarction only after symptoms stabilize, and those with high blood pressure or coronary artery disease should take care regarding blood pressure control and increased pulse rate. If signs of bleeding or blood disorders appear during use, immediate reporting and full blood count testing should be performed. Caution is advised when driving or operating machinery due to possible dizziness. Taking this medicine with food may increase blood concentration and the risk of side effects; thus, it is recommended to take it on an empty stomach and space the drug intake and meals by 3 hours. This medicine is metabolized by specific liver enzymes, so interactions with other medications may occur; caution is particularly advised when used with drugs that affect blood coagulation due to increased bleeding risk. Pregnant women, women who may become pregnant, and breastfeeding women should not use this medicine, and children or the elderly may require dosage adjustments based on physical condition. In case of overdose, symptoms such as headache, diarrhea, hypotension, tachycardia, and arrhythmias may occur, so immediate medical attention is required.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, dyspnea or difficulty breathing, asthma attacks, cough with fever accompanying respiratory abnormalities, yellowing of the skin or eyes (jaundice), extreme malaise, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Headache
• dizziness
• dyspepsia
• vomiting
• loss of appetite
• myalgia
• flushing of the face
• photosensitivity reactions
• rash
• urticaria

This medicine should be stored in a tightly closed container to prevent air or moisture from entering and kept at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the efficacy of the medication over time.

Appearance

White oblong sustained-release tablet

Package unit

Domestic - 30 tablets/bottle, Domestic - 100 tablets/bottle, Export - 5 tablets/bottle, Export - 30 tablets/bottle, Export - 100 tablets/bottle, Export - 5 tablets/PPT [(5 tablets/PPT)], Export - 10 tablets/PPT [(10 tablets/PPT)], Export - 30 tablets/PPT [(10 tablets/PPT X3)]