Desarine Capsule (Diacerein)

Adult dose

Adults: Take 50∼100mg of diacerein orally after meals in 1∼2 divided doses per day. Adjust the dose as appropriate according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily for the first 2-4 weeks is recommended, followed by 50mg twice daily.

This medication should not be used in patients with inflammatory bowel disease. For instance, patients with ulcerative colitis or Crohn's disease should not take this medication. Patients with intestinal obstruction syndrome or those experiencing unexplained abdominal pain should also avoid this medication. Individuals allergic to this medication, its components, and Rhein-class drugs should avoid this medication. Patients with liver disease or those with a history of liver disease should preferably refrain from taking this medication. Children under 15 years of age should not use this medication. Additionally, since this medication contains lactose, those with lactose intolerance or certain genetic metabolic disorders should avoid using it. Patients with a history of small intestine or colon disease should use this medication cautiously, and women who are pregnant or breastfeeding should be careful when taking this medication. Elderly patients over 65 years should take a reduced dose. This medication contains a dye called Yellow No. 5, so individuals allergic to this component should also be cautious. While taking the medication, gastrointestinal issues such as diarrhea, abdominal pain, and stomach discomfort may occur, so caution is necessary. If diarrhea worsens, dehydration or electrolyte imbalance may occur, so if these symptoms arise, immediately stop taking the medication and consult a physician. Symptoms such as skin itching, rash, and eczema can occur, so inform a healthcare provider if any unusual symptoms appear. Since it may affect liver function, if there are signs of increased liver enzyme levels or signs of liver damage, discontinue use. Long-term use should always be under a physician's direction, and alcohol consumption should be limited. Medications containing calcium, magnesium, or aluminum antacids should be taken with more than a 2-hour interval from this medication to avoid interference with its absorption. Taking diuretics with this medication may enhance diuretic effects, increasing the risk of dehydration or hypokalemia, so caution is advised. The risk of arrhythmias may increase when used with cardiac glycosides, so consultation with a healthcare provider is necessary. It is safest for pregnant or breastfeeding women to avoid this medication. In case of overdose, severe diarrhea may occur, and appropriate treatment such as electrolyte replenishment is required.

Diarrhea, loose stools, abdominal pain, gastrointestinal disorders (hemorrhage, ulcers, and perforation), pigmentation of the rectal mucosa, dehydration, fluid and electrolyte imbalance, itching, rash, eczema, elevated serum liver enzymes

This medication is sensitive to air and moisture, so it should be stored in a sealed container. It is best to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

A hard capsule with a yellow upper part and a light yellow lower part containing a brownish-yellow powder.

Package unit

30 capsules/bottle, 300 capsules/bottle