Lapuzone Tablets (Lafutidine)

Adult dose

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials in which treatment was given for up to 8 weeks, most ulcers healed within 8 weeks; however, healing time may occasionally vary from patient to patient. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials in which treatment was given for up to 6 weeks, most ulcers healed within 6 weeks; however, healing time may occasionally vary from patient to patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. In clinical trials in which treatment was given for up to 2 weeks, most lesions healed within 2 weeks; however, healing time may occasionally vary from patient to patient. 4. Concomitant antibiotic therapy in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 days or 14 days. 5. Premedication before anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine per dose twice daily.

This medication should not be used in patients with known allergies to any component of this product. It contains lactose, so it should not be used in patients with genetic lactose intolerance, lactase deficiency, or glucose-galactose malabsorption. Caution should be exercised when administering to patients with a history of allergies, liver or kidney function problems, patients undergoing dialysis, and the elderly. Rarely, severe allergic reactions or shocks may occur, and if symptoms such as pallor, low blood pressure, or difficulty breathing appear, the medication should be stopped immediately, and medical attention should be sought. Liver function abnormalities may occur, leading to elevated liver enzymes and symptoms of jaundice, so regular liver function tests are necessary, and if abnormalities are found, the medication should be discontinued. Blood cell abnormalities may occur, and if symptoms like sore throat, fatigue, or fever appear, the patient should consult a physician immediately. Rare cases of serious side effects such as skin rash, convulsions, and cardiac rhythm disturbances have been reported, necessitating immediate consultation with medical personnel in case of abnormal symptoms. Gastrointestinal symptoms may include constipation, diarrhea, nausea, vomiting, abdominal distension, and loss of appetite. Central nervous system symptoms may include headaches, insomnia, drowsiness, and dizziness. Regular blood tests are necessary as white blood cell or red blood cell counts may vary. The elderly should be administered with caution, adjusting doses and intervals due to decreased physical function. Patients undergoing dialysis may have increased blood drug concentrations, hence treatment should start at a low dose. Pregnant women should use this medication only if the benefits outweigh the risks, as determined by a physician, and breastfeeding women should avoid its use since it may be secreted in breast milk. Safety in pediatric patients has not been sufficiently established, thus caution is required in use. Keep out of reach of children, and do not transfer the medication from its original container to another container. This medication may alleviate symptoms of malignancy or delay diagnosis; therefore, if a malignancy is suspected in gastric ulcer patients, evaluation should be carried out, and if malignant gastric cancer is confirmed, the medication should be discontinued. During treatment, it is essential to closely monitor the condition of the disease and use it for only the necessary minimum period.

• Shock
• anaphylaxis symptoms
• facial pallor
• hypotension
• generalized rash
• dyspnea
• liver dysfunction
• jaundice
• agranulocytosis
• pharyngalgia

This medication may be sensitive to air and humidity, so it should be stored in a tightly sealed container. A storage temperature between 1 and 30 degrees Celsius at room temperature is recommended. This will help maintain the medication's efficacy for an extended period.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle