Esitin Tablet 10 mg (Lafutidine)

Adult dose

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials in which treatment was given for up to 8 weeks, most ulcers healed within 8 weeks; however, healing time may occasionally vary from patient to patient. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials in which treatment was given for up to 6 weeks, most ulcers healed within 6 weeks; however, healing time may occasionally vary from patient to patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. In clinical trials in which treatment was given for up to 2 weeks, most lesions healed within 2 weeks; however, healing time may occasionally vary from patient to patient. 4. Concomitant antibiotic therapy in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 days or 14 days. 5. Premedication before anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine per dose twice daily.

This medication should not be used in patients with hypersensitivity to any of its ingredients. This medication contains lactose and should not be administered to patients with genetic disorders such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. Patients with a history of allergic drug reactions, impaired liver or kidney function, those undergoing dialysis, and the elderly should use this medication with increased caution. This medication can cause severe allergic reactions or symptoms of anaphylaxis; if symptoms such as facial pallor, low blood pressure, and respiratory difficulties occur during administration, use should be stopped immediately and appropriate treatment sought. Liver function abnormalities or symptoms of jaundice may occur, hence regular liver function tests should be conducted, and the drug should be discontinued if abnormalities are found. A reduction in blood cell counts leading to agranulocytosis or thrombocytopenia may occur, so if symptoms such as sore throat, fatigue, or fever appear, medical consultation should be sought immediately. Rarely, serious side effects such as skin rashes, convulsions, or arrhythmias may occur; if any unusual symptoms arise, report them to medical staff immediately. While taking this medication, symptoms such as indigestion, nausea, headache, dizziness, and fatigue may occur. If malignant tumors are suspected, this medication may alleviate symptoms or delay diagnosis, thus when symptoms such as weight loss, recurrent vomiting, or bleeding are present, must undergo examination. Elderly patients may have decreased bodily functions, thus dosage and administration intervals should be adjusted and their condition observed carefully. Patients undergoing dialysis may have increased drug concentrations, therefore administration should start cautiously with a low dosage. Pregnant women should use this medication only if the benefits outweigh the risks as determined by a physician, and it is advised that nursing mothers avoid its use, as it may be secreted in breast milk. Safety in children has not been sufficiently established, so caution is needed in their use. This medication should be stored out of reach of children and kept in its original container to prevent misuse or degradation of quality.

• Shock
• symptoms of anaphylaxis
• facial paleness
• hypotension
• generalized pruritus
• dyspnea
• hepatic dysfunction
• jaundice
• agranulocytosis
• pharyngitis

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature. This way, the efficacy of the medication can be well preserved, ensuring safe use.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle