Udipin Tablets (Amlodipine Besylate)

Adult dose

Adults: 5 mg of amlodipine is administered orally once daily and may be increased to a maximum of 10 mg per day depending on the patient's response. The dosage should be adjusted appropriately based on age and symptoms.

This drug should not be used in certain patients. For example, individuals with allergies to this drug or similar classes of medications, pregnant women or those capable of becoming pregnant, breastfeeding women, patients with severe liver dysfunction, patients with severe aortic stenosis, and those in a state of shock should not take this medication. The drug should be used cautiously in patients with severe hypotension, patients requiring dialysis due to renal failure, and the elderly. Various side effects may occur while taking this medication; the most common symptoms include flushing, fatigue, swelling, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea. Rarely, symptoms such as excessively low blood pressure, vasculitis, neurological abnormalities, sexual dysfunction, digestive issues, increased blood sugar levels, myalgia, and skin rashes may occur, necessitating immediate consultation with a physician if abnormal symptoms appear. Patients with heart failure or impaired liver function require special caution when using this medication, as the blood pressure-lowering effect may gradually diminish even after discontinuing the medication. Therefore, when combining with other antihypertensives, the dosage and interval should be adjusted while monitoring the condition. This medication may not be effective in emergency situations such as unstable angina. Additionally, while this drug is generally not known to impair driving or machinery operation capabilities in most individuals, caution is warranted as effects may vary between individuals. This medication may interact with other drugs; therefore, it is important to inform the physician or pharmacist when taking it with certain antibiotics, antihypertensives, anticoagulants, immunosuppressants, or grapefruit juice, and to monitor carefully. Pregnant or breastfeeding women should avoid using this medication, as its safety has not been established; if necessary, it should be discussed with a physician. During breastfeeding, it is recommended to discontinue breastfeeding while taking this medication. The safety and efficacy in children have not been sufficiently established, so it should be administered cautiously to pediatric patients. Elderly patients generally tolerate the standard dosage well, but adjustments may be needed depending on individual circumstances. In cases of overdose, blood pressure may drop excessively, and heart rate may increase, requiring immediate emergency treatment, and steps to reduce drug absorption such as gastric lavage or activated charcoal may be necessary. Close monitoring of cardiac and respiratory function should be conducted, and vasoconstrictors may need to be used. This drug is not known to cause carcinogenicity or mutagenicity with prolonged use.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, difficulty breathing or shortness of breath, asthma attack, respiratory abnormalities accompanied by cough + fever, yellowing of the skin or eyes (jaundice), extreme lethargy, hepatitis, jaundice, sudden and severe headache, lightning bolt headache, seizures, confusion, visual disturbances, paralysis.

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is best to maintain a storage temperature between 1°C and 25°C.

Appearance

White round tablets

Package unit

30 tablets (PTP), 100 tablets (PTP), 300 tablets (bottle)