Musofen Tablet (Sodium Loxoprofen Hydrate)

Adult dose

1. For indications 1 and 2: ○ Adult: Take 60 mg of sodium loxoprofen (anhydrous) orally 3 times a day. For one-time treatment, take 60 to 120 mg orally. 2. For indication 3: ○ Adult: Take 60 mg of sodium loxoprofen (anhydrous) orally. In principle, it can be administered 2 times daily with a maximum of 180 mg per day. It is advisable to avoid taking it on an empty stomach.

This medication may pose a risk of gastrointestinal bleeding if taken by individuals who regularly consume three or more alcoholic drinks daily; therefore, it is essential to consult a doctor or pharmacist. This medication may increase the risk of cardiovascular diseases, with serious problems such as myocardial infarction or stroke possible, so individuals with cardiovascular diseases or risk factors should exercise particular caution. During the use of this medication, if cardiovascular symptoms arise, one should immediately consult a doctor; individuals without a history of cardiovascular disease should also carefully observe symptoms. This medication can cause severe gastrointestinal problems such as gastrointestinal bleeding, ulcers, and perforation, so those with a history of gastrointestinal diseases or elderly individuals should be especially careful. If gastrointestinal symptoms appear, one should immediately stop taking the medication and seek evaluation and treatment from a doctor. Patients with peptic ulcer, severe blood disorders, liver dysfunction, kidney dysfunction, heart failure, hypersensitivity to this medication, allergic reactions to aspirin or other non-steroidal anti-inflammatory drugs, pregnant women in late pregnancy, breastfeeding women, or patients with inflammatory bowel disease should not take this medication. Individuals with a history of peptic ulcer, blood disorders, liver dysfunction, kidney dysfunction, heart failure, a history of hypersensitivity, asthma, elderly patients, and hypertension should use this medication with caution and monitor their condition closely during use. If allergic reactions such as rash, itching, difficulty breathing, or hypotension occur during the use of this medication, one should immediately stop taking it and seek assistance from medical personnel. Gastrointestinal symptoms may include abdominal pain, nausea, vomiting, diarrhea, and blood in stool; immediate treatment is required in severe cases. This medication can cause neurological symptoms such as drowsiness, dizziness, or headaches; therefore, caution is needed while driving or operating machinery. Various adverse reactions have been reported, including liver dysfunction, kidney impairment, blood disorders, heart failure, pneumonia, and skin reactions, so one should consult a doctor immediately if symptoms arise. This medication should be used in the minimum effective dose for the shortest duration possible, and regular blood tests and liver and kidney function tests are needed during long-term use. Concurrent use with other non-steroidal anti-inflammatory drugs may increase the risk of side effects, so they should not be taken together. Interactions may occur with certain hypoglycemic agents, antibiotics, antihypertensive drugs, anticoagulants, lithium, methotrexate, etc.; therefore, one must inform their doctor about any medications they are taking. In late pregnancy, this medication could pose a risk to the fetus, so it should not be used; caution is also required during early or mid-pregnancy. It is recommended not to take this medication while breastfeeding. Safety in children has not been established, so caution is required when administering this medication to children. Elderly individuals are at a higher risk of side effects, so extra caution is advised during use. Keep this medication out of reach of children and avoid transferring it to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme drowsiness, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urinary changes.

Mild side effects

• Occasionally
• rash
• itching
• fever
• abdominal pain
• discomfort in the upper abdomen
• loss of appetite
• nausea
• vomiting
• diarrhea

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1°C and 30°C to safely preserve the medication's efficacy.

Appearance

White round tablet

Package unit

30 tablets, 300 tablets