Globeta Injection (Diclofenac Beta-Dimethylaminoethanol)

Adult administration

As diclofenac beta-dimethylaminoethanol, administer 90mg deeply into one side of the upper buttock once a day. In severe cases, 90mg may be administered twice a day, alternating injections into both buttocks. After initial treatment, switch to tablets or suppositories for administration. Adjust dosage according to age, condition, and symptoms.

This medication has the risk of causing gastrointestinal bleeding in individuals who regularly consume more than three alcoholic beverages daily, therefore it is necessary to consult a doctor or pharmacist. This medication may increase the risk of cardiovascular diseases, and serious problems like myocardial infarction or stroke may occur, so patients with cardiovascular diseases or risk factors should be especially cautious. This medication can cause serious gastrointestinal adverse effects like gastrointestinal bleeding, ulcers, and perforations, and particularly older individuals may have a higher risk of these issues, so gastrointestinal symptoms should be closely monitored during use. In cases of severe allergic reactions, symptoms similar to myocardial infarction, such as chest pain, may occur, so these symptoms should be reported to medical personnel immediately. Ampoule injections may risk contamination with glass particles, so they should be handled carefully, and special attention should be given to children and the elderly. Products containing benzyl alcohol can cause life-threatening respiratory problems in premature infants, so they should not be used in neonates or premature infants. Patients with a history of peptic ulcer, severe blood disorders, liver dysfunction, renal dysfunction, hypertension, heart failure, or hypersensitivity to any ingredient in this medication should not take this drug. Patients who have had allergic reactions to aspirin or other non-steroidal anti-inflammatory drugs should also avoid using this medication. This medication should be administered cautiously to those with a history of peptic ulcers, reduced liver or kidney function, hypertension, asthma, the elderly, and children. While taking this medication, various side effects such as headache, drowsiness, indigestion, skin rash, liver dysfunction, and renal function decline may occur, so any unusual symptoms should be reported to medical personnel immediately. For long-term use, regular blood tests and checks of liver and kidney function should be performed, and if any abnormalities are found, use should be stopped or adjusted. It should be avoided during pregnancy, especially in late stages, as it can harm the fetus, and if breastfeeding, either the medication or breastfeeding should be stopped. Due to numerous drug interactions, particularly with antihypertensives, diuretics, anticoagulants, and anticancer drugs, consultation with a doctor is essential before using this medication. The elderly and children may be particularly sensitive to side effects, so they should take the minimum effective dose with caution.

Serious side effects

• Chest pain
• chills
• difficulty breathing
• limb paralysis
• hypotension
• edema
• rash
• itching
• peptic ulcer
• gastrointestinal bleeding

Mild side effects

• Loss of appetite
• nausea
• vomiting
• abdominal pain
• diarrhea
• stomatitis
• thirst
• constipation
• headache
• drowsiness

This medication is sensitive to light and should be stored in a light-protective container. Additionally, it is best to store it at room temperature between 1 and 30 degrees Celsius.

Appearance

A brown ampoule injection containing a colorless to pale yellow transparent liquid

Package unit

2mL/ampoule x 50