Letopra 10 mg (S- Pantoprazole Sodium Trihydrate)

Adult dose

1. Treatment of non-erosive gastroesophageal reflux disease: Administer 10mg of S-pantoprazole orally once daily before breakfast. Symptom relief generally occurs within 2~4 weeks, and healing can usually be achieved with 4 weeks of treatment. 2. Long-term maintenance therapy to prevent recurrence of reflux esophagitis: Take 1 tablet once daily (equivalent to 10mg of S-pantoprazole) before breakfast. If recurrence occurs, increase the dose to 20mg of S-pantoprazole daily, then reduce it again to 10mg daily after healing.

This medication should not be used in patients with moderate to severe impairment of liver or kidney function, as safety and efficacy have not been established. Patients with a history of allergies to this medication or its components, or to benzimidazole derivatives should not use it, as it may cause severe allergic reactions such as anaphylaxis, angioedema, bronchospasm, etc. Additionally, this medication should not be taken in conjunction with certain antivirals such as atazanavir and nelfinavir, so caution is essential. It is advisable for women in the first three months of pregnancy or those who may become pregnant, as well as nursing mothers, to avoid this medication. While taking this medication, gastrointestinal symptoms such as constipation, diarrhea, gastritis, dyspepsia, and vomiting may occur, as well as rare side effects like liver dysfunction, skin rashes, headaches, and dizziness. Patients taking this medication for a prolonged period, especially for over a year, should regularly undergo health check-ups and monitor liver enzyme levels. Elderly patients or those with decreased kidney function may require dosage adjustments, and if gastroesophageal reflux disease is suspected, confirmation through endoscopy should occur before taking this medication. This medication is not recommended for neuralgic abdominal pain or mild abdominal pain. Long-term use may lead to impaired absorption of vitamin B12, and supplementation may be necessary if needed. Furthermore, long-term use may increase the risk of fractures, and caution is advised. This medication may interact with other drugs, especially anticoagulants, certain antivirals, or immunosuppressants, so it's essential to consult a physician or pharmacist if using these. If diarrhea persists or abnormal symptoms occur during treatment, consult medical personnel immediately. Swallow the tablets whole without chewing or crushing, and store them out of reach of children. Do not take during pregnancy or breastfeeding, and consult healthcare professionals if pregnancy is planned or possible. In case of overdose, there is no specific antidote, so if symptoms arise, visit a hospital immediately for appropriate treatment. This medication suppresses gastric acid secretion, which may increase bacterial counts in the stomach, thus increasing the risk of infection; caution is especially needed for hospitalized patients. The risk of developing gastric polyps may increase with long-term use, thus regular examinations are needed. Dizziness or visual disturbances may occur, so care should be taken when driving or operating machinery. In cases of prolonged use, autoimmune diseases such as cutaneous or systemic lupus erythematosus may develop, so notify healthcare professionals immediately if abnormal symptoms arise.

Anaphylaxis, anaphylactic shock, angioedema, bronchospasm, acute interstitial nephritis, urticaria, constipation, diarrhea, gastritis, gastric polyps, hiatal hernia, loose stools, chest pain, dyspepsia, nausea, vomiting, abdominal distension, enteritis, edema, fatigue, fever, sweating, hypertension, tachycardia, Eustachian tube dysfunction, dry eyes, visual impairment, cold, elevated liver enzyme levels, hyperlipidemia, insomnia, dizziness, sensory neuropathy, drowsiness, back pain, limb pain, headache, stomach pain, boils, itching, rash, nosebleed, elevated creatine phosphokinase, elevated liver enzyme level (AST), decreased appetite, stomatitis, nasal congestion, runny nose, sore throat, upper respiratory infection, neutropenia, skin lacerations, blood in stools, numbness, increased sputum, residual urine in bladder, amputation, upper abdominal pain, bloating, nausea, belching, dry mouth, weakness, lethargy, elevated body temperature, elevated bilirubin, liver failure, jaundice, anaphylactic shock, arthralgia, myalgia, rhabdomyolysis, bone fracture, headache, blurred vision, taste disturbance, sleep disorders, depression, hallucinations, confusion, disorientation, interstitial nephritis, pruritus, skin erythema, angioedema, mucous membrane syndrome, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, Riel syndrome, photosensitivity, hyperglycemia, agranulocytosis, leukopenia, thrombocytopenia, pancytopenia, gynecomastia, hyperlipidemia, increased lipids, weight changes, hyponatremia, hypomagnesemia, CK elevation, anxiety, bronchitis, increased cough, respiratory distress, flu-like symptoms, gastroenteritis, gastrointestinal disorders, hypertonia, infection, migraine, cervical pain, pain, pharyngitis, rectal disorders, rhinitis, AST elevation, sinusitis, frequent urination, urinary tract infection, allergic reactions, chills, abscess, facial edema, general edema, heat sensation, hernia, abnormal clinical laboratory test results, malaise, moniliasis, tumor, nonspecific drug reactions, electrocardiogram abnormalities, angina, arrhythmia, atrial fibrillation, coronary artery disease, congestive heart failure, bleeding, hypotension, myocardial infarction, myocardial ischemia, palpitations, retinal vascular disease, syncope, phlebitis, thrombosis, vasodilation, decreased appetite, aphthous stomatitis, colitis, duodenitis, swallowing difficulties, esophageal bleeding, esophagitis, gastric duodenal tumor, gastric duodenal bleeding, gastric duodenal moniliasis, gingivitis, halitosis, hematemesis, increased appetite, melena, oral ulcer, oral moniliasis, periodontal abscess, periodontitis, rectal bleeding, gastric ulcer, bowel irregularities, tongue discoloration, ulcerative colitis, diabetes, goiter, gallbladder pain, hyperbilirubinemia, cholecystitis, cholelithiasis, jaundice, hepatitis, ALP elevation, anemia, petechiae, eosinophilia, iron deficiency anemia, leukocytosis, thrombocytopenia, dehydration, gout, thirst, weight gain, weight loss, arthritis, bone disease, joint disease, leg cramps, bursitis, tendinitis, abnormal dream, confusion, convulsions, dry mouth, dysarthria, hyperactivity, decreased libido, anxiety, neuralgia, neuritis, neurological disorders, abnormal sensation, decreased reflex action, abnormal perception, tremors, asthma, hiccups, laryngitis, respiratory disorders, pneumonia, altered voice, acne, alopecia, contact dermatitis, eczema, fungal dermatitis, bleeding, herpes simplex, shingles, lichen planus dermatitis, papular rash, skin diseases, skin ulcers, sweating, amblyopia, cataracts, hearing loss, diplopia, otalgia, paralysis, glaucoma, otitis externa, tinnitus, albuminuria, balanitis, mastalgia, cystitis, menstrual irregularities, urination difficulties, epididymitis, hematuria, erectile dysfunction, kidney stones, renal pain, nocturia, prostate disorders, pyelonephritis, scrotal edema, urethral pain, urethral disorders, urological anomalies, vaginitis, Clostridium difficile diarrhea, DRESS syndrome, systemic lupus erythematosus, cutaneous lupus erythematosus, gastric polyp.

This medication may be sensitive to light and should be stored in a container that protects it from light. Additionally, it should be stored at room temperature, ideally between 1 and 30 degrees Celsius, to maintain its effectiveness and safety.

Appearance

Pink enteric-coated, convex, oval-shaped tablets

Package unit

28 tablets/bottle, 28 tablets/box [(7 tablets/Alu-Alu x 4)]