Medication info
Tradjenta Duo Tablet 2.5/1000 mg

Tradjenta Duo Tablet 2.5/1000 mg

Prescription medicationTablet경구
Ingredient · strength
Linagliptin›2.5mg / 1 tabletMetformin Hydrochloride›1000mg / 1 tablet
Manufacturer / importer
한국베링거인겔하임(주)
Appearance
A bright pink, biconvex, oval film-coated tablet
Packaging
60 tablets/box [(10 tablets/PTP pack x 6)]
Approval status
Active

MFDS item code 201208292 · Approved 2012.11.15 · Insurance code 653501410

Summary

Main use
Improvement in blood glucose control for type 2 diabetes
Who takes it
Adults
Adult dose
This medication is administered twice a day with meals. To reduce gastrointestinal side effects related to metformin use, dose increases should be gradual. 1. If not currently being treated with metformin: The initial dose is 2.5/500 mg of this medication, taken as 1 tablet twice daily, and it can be increased to 2.5/1000 mg, taken as 1 tablet twice daily. 2. If blood sugar is not adequately controlled with metformin alone:

Ingredients

Importer
한국베링거인겔하임(주)

Efficacy & effects

Improvement in blood glucose control for type 2 diabetes

View approved original text

This medication helps patients with type 2 diabetes to control their blood sugar more effectively. It is particularly suitable for those who follow dietary and exercise therapy, enhancing blood glucose control through the combination of linagliptin and metformin, thus supporting health management. This medication significantly aids in the management of diabetes by improving blood glucose control.

How to take

Adult dose

This medication is administered twice a day with meals. To reduce gastrointestinal side effects related to metformin use, dose increases should be gradual. 1. If not currently being treated with metformin: The initial dose is 2.5/500 mg of this medication, taken as 1 tablet twice daily, and it can be increased to 2.5/1000 mg, taken as 1 tablet twice daily. 2. If blood sugar is not adequately controlled with metformin alone:

Precautions

This medication is a drug that helps control blood sugar. However, there are several important precautions you must know before taking this drug. First, one of the active ingredients, metformin, can cause a rare but serious side effect known as lactic acidosis. Lactic acidosis occurs when there is an excessive buildup of lactic acid in the body, which can be life-threatening if not treated, so you should seek immediate medical attention if symptoms appear. Second, this medication should not be administered to certain patients. For example, individuals allergic to this drug or its components, patients with type 1 diabetes, patients with severe kidney dysfunction, patients with acute heart issues or severe infections, as well as pregnant or breastfeeding women should not take this medication. Third, there is a risk of hypoglycemia with this medication, so blood sugar changes should be closely monitored, especially when taken with sulfonylureas or insulin. Additionally, patients with decreased kidney function should undergo regular kidney function tests, and those with significantly impaired kidney function should not take this medication. Fourth, rare skin conditions such as acute pancreatitis or bullous pemphigoid may occur while taking this medication, so if you experience severe abdominal pain or develop blisters on the skin, you should consult with a healthcare professional immediately. Fifth, metformin can lower vitamin B12 levels, so it is necessary to regularly check for vitamin B12 deficiency if taking this drug over the long term. Sixth, this medication may interact with other drugs, so you must inform your doctor or pharmacist of any medications you are currently taking. Special caution is needed when taken with drugs that may affect kidney function, certain antibiotics, diuretics, or antihypertensives. Seventh, women who are pregnant or planning to become pregnant are advised not to take this medication, and it should be avoided during breastfeeding as well. Eighth, this medication is not recommended for children or those under 10 years of age, as its safety and efficacy have not been established in this population. Ninth, there may be a risk of decreased kidney function in the elderly, so appropriate dose adjustments and regular kidney function tests are necessary. Finally, in case of overdose, serious side effects such as gastrointestinal disturbances or lactic acidosis may occur, so you should strictly adhere to the dosage guidelines, and if an overdose is suspected, seek immediate medical attention. Store this medication out of reach of children and avoid humidity when storing it. Also, it is safer to avoid transferring it to other containers. If you follow all these precautions carefully, this medication can help control blood sugar levels. If you experience any abnormal symptoms while taking it, consult with a healthcare professional immediately.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema, lactic acidosis, pancreatitis, bullous pemphigoid, hepatic dysfunction (abnormal liver function tests, hepatitis), severe allergic reactions (hives, angioedema), serious neurological symptoms, respiratory problems (dyspnea, asthma), severe edema and urination abnormalities (facial edema), severe skin reactions (rash, bullous pemphigoid), severe swelling, acute myocardial infarction, acute myocardial infarction syndrome, angina, unstable angina, and severe reactions.

Mild side effects

  • Nasopharyngitis
  • hypersensitivity
  • hypoglycemia
  • taste disturbance
  • cough
  • reduced appetite
  • diarrhea
  • constipation
  • nausea
  • vomiting
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  • abdominal pain
  • abnormal liver function tests
  • hepatitis
  • pruritus
  • erythema
  • rash
  • oral ulcer formation
  • increased lipase
  • increased amylase
  • oral ulcers
  • itching
  • headache
  • dizziness
  • paresthesia
  • drowsiness
  • fatigue
  • chest discomfort
  • weakness
  • nosebleed
  • oropharyngeal pain
  • voice disorders
  • runny nose
  • musculoskeletal discomfort
  • myositis
  • myalgia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to air and moisture, so it should be stored in a tightly sealed container. Additionally, it is important to store it at room temperature between 1 to 30 degrees Celsius to maintain its effectiveness.

Appearance and packaging

Appearance

A bright pink, biconvex, oval film-coated tablet

Package unit

60 tablets/box [(10 tablets/PTP pack x 6)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.