Asterin Tablet (Aspirin)

Adult dose

(Enteric-coated tablets) Adults: 1 tablet once daily, do not take high doses without a doctor's prescription. (Enteric-coated capsules) Adults: 1 capsule once daily, do not take high doses without a doctor's prescription.

This drug may cause an increased risk of gastrointestinal bleeding in individuals who regularly consume more than three alcoholic beverages daily; therefore, it is important to consult a doctor or pharmacist. This medication should not be administered to certain patients, including those with a known allergy to this drug or other salicylates, patients with peptic ulcers, asthmatic patients sensitive to aspirin, patients with hemophilia, severe liver or kidney dysfunction, severe heart failure, patients with a tendency to bleed, those taking high doses of methotrexate, and pregnant women in the third trimester. Additionally, caution is advised when administering this drug to patients with kidney dysfunction, cardiovascular circulation abnormalities, liver disorders, blood disorders, bronchial asthma, pre-surgical patients, children under three years of age, patients with allergy histories, elderly patients, those taking anticoagulants, and patients with glucose-6-phosphate dehydrogenase deficiency. Various adverse reactions may occur during the use of this medication, such as shock, anaphylaxis, skin rashes, blood disorders, gastrointestinal symptoms, neurological symptoms, liver impairment, and kidney dysfunction; thus, patients' conditions should be observed carefully. In particular, there is a risk of serious side effects such as Reye's syndrome in children under 14 years of age, so caution should be exercised when administering to those with chickenpox or influenza. During chronic disease treatment, regular blood tests and liver function tests should be performed, and if abnormalities are noted, dosing should be halted or adjusted. In acute diseases, dosing should be based on the severity of symptoms, and long-term use should be avoided. Because this drug increases the risk of bleeding, special care is required before and after surgery, and overdose can lead to severe toxicity symptoms. Moreover, this drug may interact with multiple medications; thus, a consultation with a doctor or pharmacist is essential if other medications are being taken. In pregnancy, especially in the third trimester, this drug may pose risks to the fetus and the mother, so its use should be avoided. In breastfeeding, this drug transfers into breast milk, so it is safest not to take it. Elderly patients may experience adverse reactions more easily, so starting with a lower dose and careful administration is advisable. Finally, this drug should be kept out of reach of children, stored in its original container, and not mixed with other medications.

Serious side effects

• Hives, severe swelling (angioedema), chest tightness, difficulty breathing (dyspnea), cold sweat, pallor (anaphylaxis symptoms)
• Severe skin reactions: Severe rash accompanied by high fever, blisters, skin peeling, pain in the oral/ocular mucosa (Lyell syndrome, Stevens-Johnson syndrome, exfoliative dermatitis, DRESS syndrome)
• Respiratory issues: Asthma attacks
• Blood disorders: Aplastic anemia, anemia, leukopenia, thrombocytopenia

Mild side effects

Skin redness, itching, nasal congestion, rash, swelling, symptoms of rhinitis, conjunctivitis, loss of appetite, heartburn, stomach pain, nausea, vomiting, tinnitus, hearing impairment, dizziness, headache, excitement, temporary liver damage due to increased liver transaminases, hyperventilation, metabolic acidosis

Drug interactions

This drug may increase the risk of bleeding or decrease renal function when used in combination with other non-steroidal anti-inflammatory drugs and salicylates. Anticoagulants, ibuprofen, naproxen, and some other non-steroidal anti-inflammatory drugs, thrombolytic agents, other platelet aggregation inhibitors, hemostatics, diabetes medications (insulin, tolbutamide, etc.), uricosuric agents (benzbromarone, probenecid), thiazide diuretics, lithium preparations, selective serotonin reuptake inhibitors and certain other medications may interact.

This medication can be sensitive to air and moisture; therefore, it should be stored in a tightly closed container. Furthermore, it is advisable to store the drug at room temperature below 25 degrees Celsius to maintain its efficacy.

Appearance

White, round, enteric-coated film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle