Amrovis Tablet (Amlodipine Besilate)

Adult dose

Adults: Take 5mg orally once daily, with the dose potentially increased to a maximum of 10mg daily based on patient response. Adjust as necessary according to age and symptoms.

This medication should not be used in certain patients. For example, individuals who are allergic to this medication or similar drugs, those who are breastfeeding, patients with severely impaired liver function, those with severe aortic stenosis, and individuals in a state of shock should not take this medication. Additionally, patients with severe hypotension, those requiring dialysis due to renal failure, elderly individuals, and women who are pregnant or may become pregnant should use this medication with caution. Various side effects may occur while taking this medication. The most common side effects include facial flushing, fatigue, swelling, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea. Rarely, symptoms such as excessively low blood pressure, vasculitis, neurological abnormalities, erectile dysfunction, gynecomastia, dry mouth, weight changes, skin rash, and hair loss may occur. If these adverse reactions appear, immediate consultation with healthcare professionals is required. Caution is advised for patients with weakened heart function, as this medication may cause issues like pulmonary edema. Patients with impaired liver function may also require dosage adjustments due to prolonged effects of this medication. This medication has a gradual effect on lowering blood pressure; thus, it is not suitable for urgent situations like acute angina. It is known not to significantly affect the ability to drive or operate machinery, although individual responses may vary, requiring caution. Co-administration with other medications may result in interactions. Particularly, consuming grapefruit juice alongside this medication may enhance its blood pressure-lowering effects, so it is advisable to avoid it. Furthermore, when taken with specific antibiotics, antihypertensive medications, or diuretics, it is essential to follow the guidance of healthcare professionals, as drug interactions may increase the risk of side effects. Women who are pregnant or breastfeeding should avoid using this medication unless there are exceptional circumstances, and during breastfeeding, it is recommended to discontinue breastfeeding while taking this medication. In pediatric cases, this medication may be used for children aged 6 years and older, with confirmed blood pressure-lowering effects in this age group. In the case of overdose, excessively low blood pressure and increased heart rate may occur, necessitating immediate emergency treatment. Because this medication is not removed through hemodialysis, caution is required. This medication has been reported to have a low risk of carcinogenicity or genotoxicity and is generally safe for long-term use. Before taking this medication, it is imperative to consult with healthcare professionals for proper usage tailored to individual health conditions and any other medications being taken.

Serious side effects

• Rash
• angioedema
• erythema multiforme
• toxic epidermal necrolysis
• hepatitis
• jaundice
• severe swelling
• respiratory distress
• syncope
• severe hypotension

Mild side effects

• Flushing
• fatigue
• swelling
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication is sensitive to light; therefore, it should be stored in a container that does not allow light to enter. Additionally, it should be stored at room temperature, between 1 to 30 degrees Celsius, avoiding excessively hot or cold places.

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 500 tablets/bottle