Arostin 10 mg Tablet (Atorvastatin Calcium Trihydrate)

Adult dose

1. Hyperlipidemia: The recommended initial dose is 10 mg atorvastatin once daily; however, for patients requiring greater reductions in LDL cholesterol, it may be initiated at 20 mg or 40 mg once daily. The dose range for this medication is 10 to 80 mg once daily. For patients with homozygous familial hypercholesterolemia: The dosing regimen for this medication is once daily at 10 to 80 mg, either in conjunction with other lipid-lowering therapies (e.g., LDL apheresis) or when such therapies are not feasible.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10-17): The recommended initial dose of this medication is 10 mg once daily, and the recommended maximum dose is 20 mg once daily. Dosage adjustments should be made according to individual patient needs.

This medication carries a risk of muscle problems; therefore, it should be discontinued immediately if there is worsening muscle pain or weakness, or a significant increase in creatine kinase levels. Patients with impaired liver function or a history of liver disease should not use this medication and should undergo regular liver function tests. Women who are pregnant, may become pregnant, or are breastfeeding should not use this medication, and fertile women should take appropriate contraception while on the drug. Children, particularly those under 10 years of age, should not take this medication, and long-term safety in individuals under 18 has not been well studied. This drug should be used with extra caution in patients with a history of alcohol abuse, liver disease, renal impairment, and elderly patients, as there is a higher risk of serious side effects such as myopathy or rhabdomyolysis; careful monitoring is necessary. Due to possible interactions with other medications, special caution is needed, especially when taken with CYP3A4 inhibitors, cyclosporine, some antibiotics, antifungals, HIV protease inhibitors, grapefruit juice, etc. Patients experiencing symptoms such as muscle pain, muscle weakness, fever, or malaise should notify their doctor immediately and undergo examination; in severe cases, the medication should be discontinued. This drug may cause various side effects such as liver function abnormalities, skin rashes, allergic reactions, gastrointestinal symptoms, and neurological symptoms, so consult healthcare professionals if any abnormal signs occur. There is no specific antidote for overdose, so treatment should be symptomatic and liver function and muscle enzyme tests must be conducted to manage the condition. This medication should be kept out of reach of children and stored in its original container tightly closed.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urinary retention

Mild side effects

• Weakness
• malaise
• chest pain
• peripheral edema
• fatigue
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This drug may be sensitive to air and moisture, so it must be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 and 30 degrees Celsius. This will help maintain the medication's effectiveness and safety over time.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle