Hyaluronic Acid Joint Injection (Sodium Hyaluronate)

Adult administration

For adults, administer one syringe once a week for three consecutive weeks into the knee joint or shoulder joint, adjusting the number of doses according to symptoms.

This medication should not be used in patients with a history of allergic reactions to its components. Patients with a history of allergies to other medications, those with liver function problems or previous liver disorders, and those with skin diseases or infections at the injection site should use this medication with caution. Using this medication may result in allergic reactions such as swelling of the face or around the eyes, rash, and itching; if these symptoms occur, discontinue use immediately and seek appropriate treatment. Transient pain, swelling, redness, warmth, and severe pressure sensation at the injection site may occur, requiring caution. Other symptoms such as nausea, vomiting, and fever may also arise. In cases of significant joint inflammation, it's advisable to wait until the inflammation subsides before using this medication. After administration, stabilizing the injection site and ensuring that the medication does not leak outside the joint is necessary. Injections should only be accurately administered within the knee joint in a sterile environment, and if symptoms do not improve, administration should be limited to three times and then discontinued. If there is excess joint fluid, it should be drained if necessary prior to administration. This medication should not be used intravascularly or directly in the eyes, and an appropriately sized syringe needle must be used. Additionally, care should be taken as mixing with certain disinfectants may cause the medication to precipitate. For pregnant women or those who may become pregnant, this medication's safety has not been fully established; it should be used only with caution when the benefits of treatment outweigh the risks. Nursing mothers should avoid breastfeeding during treatment since this medication may be transmitted in breast milk. Use in children should only be done with caution as its safety has not been established. Elderly patients may have reduced bodily function, hence special attention should be paid during use.

Serious side effects

Shock (severe allergic reaction)

Mild side effects

• Hypersensitivity
• swelling (facial, eyelid, etc.)
• facial flushing
• rash
• hives
• itching
• transient pain
• distension
• edema
• redness

This medication should be stored in a sealed container to prevent air contamination, and it is advisable to keep it at room temperature between 1 and 30 degrees Celsius. This storage method will help maintain the efficacy of the medication.

Appearance

A colorless, transparent, viscous liquid contained in a colorless, transparent glass syringe, sealed at both ends with rubber stoppers (part of a prefilled syringe system).

Package unit

3 syringes/box (2ml/syringe × 3)