Azuroksone (Loxoprofen Sodium Hydrate)

Adult dose

1. For indications 1 and 2: Take 60 mg orally three times a day. For single-dose therapy, take 60–120 mg orally. 2. For indication 3: Take 60 mg orally. In principle, it can be dosed twice a day, with a maximum daily dose of 180 mg. It is advisable to avoid taking it on an empty stomach. Adjust as appropriate according to symptoms.

This medication should be consulted with a doctor or pharmacist before use for individuals who regularly consume more than three glasses of alcohol a day. The risk of gastrointestinal bleeding may increase in those who frequently consume alcohol while taking this medication. This medication can impact the cardiovascular system, increasing the risk of serious thrombotic reactions such as heart attacks or strokes. Caution is especially needed for individuals with cardiovascular diseases or risk factors, and if symptoms occur, immediate medical attention should be sought. This medication can cause gastrointestinal side effects, including risks of gastrointestinal bleeding, ulcers, and perforations. Such issues can occur without symptoms, so careful monitoring of individuals, especially the elderly or those with a history of gastrointestinal disorders, is necessary during usage. People with a history of peptic ulcers, severe blood disorders, very poor liver or kidney function, and heart failure should not take this medication. Those with allergies to this medication or its components, or with a history of asthma or allergic reactions to aspirin or other anti-inflammatory analgesics, should also avoid it. Pregnant women in late pregnancy and breastfeeding mothers, as well as individuals with specific genetic lactose intolerance, should not use this medication. Individuals with a history of peptic ulcers, liver, kidney, or blood disorders, the elderly, and hypertension patients should take this medication with caution. Pregnant women in the early and mid-pregnancy should consult a doctor before use. This medication can cause allergic reactions such as skin rash, hives, and difficulty breathing, which can lead to shock or anaphylaxis in severe cases. Gastrointestinal symptoms may include gastric ulcer, bleeding, and abdominal pain, so usage should be stopped immediately and medical attention sought if these symptoms occur. Additionally, various side effects such as drowsiness, dizziness, headaches, anemia, liver dysfunction, and kidney failure have been reported, so any abnormal symptoms during treatment should be consulted with healthcare professionals. This medication should not be taken in conjunction with other non-steroidal anti-inflammatory drugs due to increased risk of side effects. Interactions may also occur with various medications such as antidiabetics, antibiotics, antihypertensives, and anticoagulants, so if you are taking other medications, it is essential to inform your doctor. Usage during pregnancy, particularly in late stages, should be avoided. Women of childbearing potential should consider the risks and benefits carefully and use the lowest dose for the shortest duration necessary. It is advisable for nursing mothers not to take this medication. The safety of this medication in children has not been established, so its use in pediatric patients is not recommended. Elderly patients are at increased risk of side effects and should be especially cautious while using this medication. This medication should be stored out of reach of children, and care should be taken as transferring it to other containers may reduce its quality.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by high fever, blisters, peeling skin, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory distress accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, coma

Mild side effects

• Occasionally
• rash
• itching
• fever
• abdominal pain
• discomfort in the stomach
• loss of appetite
• nausea
• vomiting
• diarrhea

This medication should be stored in a sealed container to prevent air or moisture from entering, and it is best kept at room temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness over time.

Appearance

White round tablets

Package unit

30 tablets/bottle, 500 tablets/bottle