Ibandronate Sodium Hydrate Tablets

Adult dose

Take 1 tablet once a month regularly on the same morning at least 1 hour prior to consuming food, drinks (excluding water), or other oral medications or dietary supplements (including calcium) with a sufficient amount of water. - The tablet should be swallowed upright or in a sitting position with a sufficient amount (180-240ml) of water, and you should not lie down for 60 minutes after taking it. - Carbonated mineral water may reduce the absorption of this medication.

Child dose

Efficacy and safety in children under 18 years have not been studied.

This medication should not be used in certain patients. Patients who are allergic to this drug or its components, those with untreated hypocalcemia, patients who cannot remain sitting or standing upright for long durations, those with esophageal dysfunction making it difficult for food to pass, and patients with genetic issues like lactose intolerance should not take this medication. In patients with severe renal failure, this medication should be used cautiously and physician evaluation is required. Gastrointestinal side effects may occur, such as dyspepsia, nausea, abdominal pain, and diarrhea. Symptoms like headache, muscle pain, fatigue, and rash have also been reported. Particularly, this drug may irritate the esophagus, leading to difficulty swallowing, pain, chest pain, or heartburn. If such symptoms occur, discontinue the medication immediately and consult a physician. It is important to take this drug with calcium and vitamin D. Since absorption may be hindered if taken with milk, calcium supplements, antacids, iron supplements, etc., it is advised to not eat or take other medications for at least 1 hour after taking this medication. Osteonecrosis of the jaw is a serious side effect that can occur rarely, hence dental treatment should be discussed with your doctor beforehand, and excessive dental work should be avoided during treatment. This medication is not recommended for use in women who are pregnant or breastfeeding. Long-term use may rarely lead to atypical femoral fractures; therefore, if there is pain in the thigh or groin, a visit to the hospital should be made for examination without delay. This medication has not been proven safe or effective in children, therefore it should not be used. In case of overdose, gastrointestinal disturbances or hypocalcemia may occur, thus exact dosing should be adhered to and healthcare professionals should be contacted immediately in case of any side effects. Finally, this medication should be kept out of reach of children, and expired medicines should be disposed of properly to prevent environmental pollution.

Serious side effects

Hives, severe swelling (edema), angioedema, chest tightness, difficulty breathing, anaphylactic reactions/shock, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in the mucous membranes of mouth/eyes, Stevens-Johnson syndrome, erythema multiforme, vesicular dermatitis, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities along with cough and fever, yellowing of the skin or eyes (jaundice), general malaise, acute renal failure

Mild side effects

• Dyspepsia
• nausea
• abdominal pain
• diarrhea
• bloating
• gastroesophageal reflux disease
• headache
• influenza-like illness
• fatigue
• muscle pain

This medication should be stored in a sealed container to protect it from air and moisture. It is important to maintain storage temperatures between 1 to 30 degrees Celsius.

Appearance

White to almost white oblong film-coated tablets

Package unit

1 tablet per blister