Epeshina Tablets (Eperisone Hydrochloride)

Adult dose

Administer 50 mg of Eperisone Hydrochloride orally three times a day after meals. Adjust dosage according to age and symptoms.

This medication should not be used in certain patients. First, it should not be administered to patients who have previously had allergic reactions to this drug or to patients with severe muscle weakness. Additionally, since this medication contains lactose, it should not be used in patients with genetic disorders affecting lactose breakdown. Extra caution should be taken when administering this drug to patients with a history of hypersensitivity or those with impaired liver function. Since liver function may deteriorate, these patients should be treated under medical observation. When using this medication, rare but serious shock reactions may occur, so symptoms should be monitored closely. Regular tests are necessary as liver function test results may increase or renal function abnormalities may occur. Allergic symptoms such as anemia, skin rash, and itching may also occur. Neurological symptoms may include insomnia, drowsiness, headache, and limb paralysis, while gastrointestinal symptoms may include nausea, vomiting, loss of appetite, and abdominal pain. Urinary symptoms, such as urinary disorders, may occur rarely. Systemically, weakness, dizziness, and reduced muscle tension may also arise; thus, caution is warranted. This medication can induce severe skin conditions such as toxic epidermal necrolysis syndrome and Stevens-Johnson syndrome; therefore, if any abnormal skin symptoms occur, the drug should be discontinued immediately and a doctor should be consulted. During treatment with this drug, weakness, staggering, and drowsiness may occur; it is advisable to reduce or discontinue the dosage if such symptoms manifest. As drowsiness or decreased concentration may occur, activities such as driving or operating dangerous machinery should be avoided. Caution is necessary when taking this drug in combination with similar medications such as tolperisone hydrochloride or methocarbamol as issues with motor control may arise. Pregnant women or those who may become pregnant should only use this drug when the therapeutic benefit exceeds the risk, as its safety has not been established. Breastfeeding women should avoid this medication whenever possible; if it must be used, breastfeeding should be discontinued. The safety of this drug in children has not been sufficiently established, so it should be used with caution. In elderly patients, caution should also be taken as bodily functions may be reduced, and dosages may need to be adjusted.

Serious side effects

Shock (severe allergic reaction), anaphylactic reaction (severe allergic reaction), angioedema (severe swelling), toxic epidermal necrolysis and mucocutaneous-ocular syndrome (severe skin adverse reactions), liver disorders (liver abnormalities due to elevated ALT, AST, ALP), kidney abnormalities (proteinuria, elevated BUN), anemia, edema

Mild side effects

• Rash
• itching
• insomnia
• drowsiness
• headache
• limb paralysis
• muscle stiffness
• limb tremors
• nausea
• vomiting

This medication should be stored in a tightly closed container that is not exposed to air, kept at a temperature between 1 degree and 30 degrees Celsius. This helps maintain the drug's efficacy and safety.

Appearance

[For domestic use] White round tablet [For export] White round film-coated tablet

Package unit

[For domestic use] 30 tablets/bottle, 500 tablets/bottle, [For export] 100 tablets (10 tablets/PTP X 10)