Roxpin Tablets (Sodium Loxoprofen Hydrate)

Adult dose

The usual adult dosage is 60 mg taken orally three times a day. For a single treatment, 60-120 mg is administered orally. In principle, it can be given twice a day, with a maximum of 180 mg per day. It is advisable to avoid taking it on an empty stomach and to adjust the dosage according to symptoms.

This medication should be consulted with a doctor or pharmacist if the patient regularly consumes more than three alcoholic beverages a day as it may pose a risk of stomach bleeding. Patients with cardiovascular diseases or risk factors should be cautious as serious cardiovascular issues such as myocardial infarction or stroke may arise while taking this medication. It may lead to severe problems in the stomach or intestine such as bleeding, ulcers, or perforation, especially in the elderly. Patients with a history of peptic ulcers, severe blood disorders, liver dysfunction, kidney disorders, congestive heart failure, or those allergic to this medication or its components should not take this drug. Pregnant women in the late stages and breastfeeding mothers, as well as patients with inflammatory bowel disease, are advised not to use this drug. Those with a history of peptic ulcers, blood disorders, liver dysfunction, kidney disorders, heart failure, allergic history, asthma, high blood pressure, and the elderly should use this medication with caution. This drug may cause allergic reactions such as skin rash, itching, and hives, so it should be discontinued immediately at the onset of symptoms. Gastrointestinal symptoms such as abdominal pain, nausea, vomiting, diarrhea, etc. may occur, and in severe cases, bleeding or perforation may happen, so careful observation is necessary. Symptoms of dizziness, drowsiness, and headache may occur, requiring caution when driving or operating machinery. Long-term use may affect liver and kidney functions, so regular blood tests and liver and kidney function checks should be performed. The risk of side effects increases when taken with other non-steroidal anti-inflammatory drugs, so it is advisable not to combine them. There may be interactions with specific blood pressure medications, anticoagulants, diuretics, antibiotics, and antineoplastic agents, so it is essential to inform about any other medications being taken. The use of this medication should be avoided during pregnancy, especially in the late stages, as it may pose risks to the fetus, and women who might become pregnant should take it with caution. This drug’s safety for children has not been established, so it is safe not to use it in children. The elderly are at higher risk for adverse reactions, making caution during use essential. This medication should be stored out of the reach of children, and it is advisable not to transfer it to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, shock, anaphylaxis-like symptoms, peptic ulcers, perforation, hematemesis, hematochezia, abdominal pain, respiratory distress, skin and mucous membrane syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), erythema multiforme, acute generalized exanthematous pustulosis, jaundice, liver dysfunction, fulminant hepatitis, acute renal failure, interstitial nephritis, respiratory distress, asthma attack, interstitial pneumonia

Mild side effects

• Occasionally rash
• itching
• fever
• abdominal pain
• discomfort in the upper abdomen
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, ideally at a temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness.

Appearance

White round tablet

Package unit

Bottle - 30 tablets/bottle, Bottle - 300 tablets/bottle