Celecox Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be administered regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib per dose, twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment at 400 mg per day, another treatment method should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

Caution is advised when taking this medication if you consume alcohol excessively daily, as it may increase the risk of gastrointestinal bleeding; consult a doctor or pharmacist. This medication can increase the risk of cardiovascular diseases such as heart attacks or strokes, so it should be used at the lowest effective dose for the shortest duration. If symptoms such as chest pain, shortness of breath, weakness, or slurred speech occur while taking this medication, seek medical attention immediately. Gastrointestinal ulcers or bleeding could occur, so report symptoms like abdominal pain, indigestion, black stools, or vomiting blood to medical personnel promptly. Elderly patients or those with a history of gastrointestinal diseases are at a higher risk for gastrointestinal-related side effects, and caution is warranted. Those with allergies or asthma, severe liver or kidney disease, active peptic ulcer disease, heart failure, pregnant or breastfeeding women should not take this medication. A careful assessment is required for patients with compromised liver or kidney function, hypertension, heart failure, or diabetes, and regular monitoring is necessary. This medication can cause various side effects; the most common include indigestion, headache, dizziness, hypertension, cough, and skin rash. If severe skin rash, difficulty breathing, swelling of the face or lips occurs, stop taking the medication immediately and seek emergency treatment. This medication can interact with other medications, so inform your healthcare provider of any other medications you are taking. Pregnant women or those planning to become pregnant should avoid using this medication, and breastfeeding women should consult a specialist before use. The safety and efficacy of this medication have not been established in children and adolescents. Elderly patients may have decreased kidney and liver function, necessitating closer observation during use. If dizziness or drowsiness occurs during treatment, it is advisable to avoid driving or operating machinery. Regular blood tests and liver and kidney function tests are recommended for those taking this medication long-term, and any unusual symptoms should be reported immediately to healthcare professionals.

Gastrointestinal bleeding, cardiovascular thrombotic response, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle rigidity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial swelling, influenza-like illness, damage, taste disturbance, albuminuria, cystitis, hematuria, dysuria, frequency of urination, nephrolithiasis, incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, retinal artery or vein occlusion, elevated serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, menstrual disorders, chest pain, headache, dizziness, constipation, thirst, ulcerative stomatitis, gastritis, allergy, back pain, hyperlipidemia, diabetes, weight gain, fracture, arthralgia, RA factor positive, herpes zoster, pneumonia, dyspnea, elevated ALT, hearing loss, anaphylactic reaction, hallucination, intracerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitive reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized pustular rash, exfoliative dermatitis, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change disease glomerulonephritis, female infertility

Store this medication in a tightly sealed container to prevent air or moisture from entering. It is best to maintain storage temperatures between 15 to 30 degrees Celsius.

Appearance

White to off-white powder in a white hard capsule with yellow stripes on the upper and lower parts

Package unit

Military supply - 100 capsules/bottle, Domestic use - 30 capsules/bottle, Domestic use - 100 capsules/bottle, Export - 10 capsules/PTP[(10 capsules/PTPX1)], Export - 30 capsules/PTP[(10 capsules/PTPX3)]