Caduet Tablets 10/20 mg (Amlodipine Besylate / Atorvastatin Calcium Trihydrate)

Adult dose

This medication is for adult use only, and the dosage should be individualized based on the efficacy and tolerability of amlodipine/atorvastatin for each patient. Amlodipine (S-amlodipine): Take 5 (2.5) mg orally once daily, and the dose can be increased up to a maximum of 10 (5) mg daily according to the patient's response. Atorvastatin: For patients with primary hypercholesterolemia and mixed dyslipidemia, the recommended initial dose is 10 mg once daily, but for patients requiring more LDL cholesterol reduction, it may be started at 20 mg or 40 mg once daily (only if a reduction of more than 45% in LDL cholesterol is needed). This medication is administered in a dosage range of 10 mg to 80 mg once daily and can be taken at any time with or without food. The initial and maintenance doses of this medication should be individualized according to treatment goals and response, and lipid levels should be analyzed and dosage adjusted within 2 to 4 weeks after initiation or dose adjustment.

This medication should not be administered to certain patients. For example, patients who are allergic to this medication or similar drugs, those with severely impaired liver function, pregnant or breastfeeding women, patients with muscle diseases, severe aortic stenosis, patients in shock, severely hypotensive patients, those who have recently experienced a myocardial infarction, patients with unstable angina, and patients currently taking certain antiviral drugs should not use this medication. Furthermore, patients with very poor kidney function, the elderly, alcoholics, those with a history of liver disease, patients with risk factors for muscle diseases, those with acute heart failure, hypertensive crisis patients, patients with mild to moderate liver dysfunction, and those with severe myasthenia should use this medication with extra caution. Side effects that may occur while taking this medication include flushing due to vasodilation, fatigue, edema, palpitations, dizziness, headache, drowsiness, dyspepsia, myalgia, arthralgia, etc. Rarely, serious adverse reactions such as liver dysfunction, skin rash, allergic reactions, and muscle damage can occur, so it is essential to notify medical personnel immediately if symptoms appear. Women who are pregnant or may become pregnant should not take this medication, and if pregnancy is confirmed while taking it, it should be discontinued immediately. Breastfeeding women should also avoid taking this medication. This medication may interact with other drugs, so if there are drugs currently being taken, it is essential to inform medical personnel, particularly when combining with certain antibiotics, antifungals, antivirals, immunosuppressants, antihypertensives, or antidiabetic medications. In the case of an overdose, severe hypotension, shock, and cardiac functional abnormalities may occur, so immediate emergency treatment must be sought, as it is generally not removed by hemodialysis. This medication has not been fully established for safety and effectiveness in children and the elderly, so it should be used under the guidance of medical personnel. Finally, this medication should be kept out of reach of children and should not be transferred to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, peeling skin, oral/ocular mucosa pain, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowness of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, urinary issues

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a temperature between 15 and 30 degrees Celsius at room temperature. This helps to preserve the medication's effectiveness for a longer time.

Appearance

Blue oval film-coated tablet

Package unit

30 tablets/bottle