Atorban Tablet 10 mg (Atorvastatin Calcium Hydrate)

Adult dose

For treatment of hyperlipidemia, the recommended starting dose is 10 mg of atorvastatin once daily; for patients requiring greater reductions in LDL cholesterol, starting doses may be increased to 20 mg or 40 mg once daily. Doses range from 10 to 80 mg once daily. Lipid levels should be assessed within 2 to 4 weeks following initiation and dose adjustment to determine further dosage modifications. For patients with homozygous familial hypercholesterolemia, doses are typically within the range of 10 to 80 mg once daily, often in conjunction with other lipid-lowering therapies (e.g., LDL apheresis) when this is not feasible. For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17 years), the recommended starting dose is 10 mg once daily with a maximum recommended dose of 20 mg per day (there is no clinical data for doses over 20 mg in this population). Adjustments should be made based on individual patient response to the recommended treatment goals, with dosage being adjusted at intervals of 4 weeks or more. ○ In patients with renal impairment: Renal disease does not affect the plasma concentration or LDL cholesterol-lowering efficacy of atorvastatin, so no dose adjustment is necessary. ○ In the elderly: Efficacy and safety in patients aged 70 years and older are similar to those in the general adult population.

Child dose

The recommended starting dose for pediatric patients with heterozygous familial hypercholesterolemia (ages 10-17 years) is 10 mg once daily, with a maximum dose of 20 mg per day. Dosage adjustments should be made at intervals of 4 weeks or more.

This medication may pose a risk of muscle problems, so if muscle pain or weakness occurs, consult a doctor immediately. This medication may affect liver function; therefore, it should not be used if there is liver disease or elevated liver enzyme levels. Women who are pregnant or may become pregnant, as well as nursing mothers, should not take this medication. Children, especially those under 10 years old, should not use this medication, and children aged 10 to 17 should use it cautiously under a doctor’s guidance. Patients with a history of alcohol abuse or liver disease need to exercise caution when taking this medication. This medication may interact with other drugs; therefore, inform your doctor or pharmacist about any other medications you are taking. Particularly, there is an increased risk of muscle damage when combined with certain antibiotics, antifungals, and antivirals, so caution is advised. During the course of this medication, it is important to regularly monitor liver function and muscle condition. If severe muscle pain, muscle weakness, fatigue, or fever occurs, inform your healthcare provider and undergo testing immediately. Taking this medication with grapefruit juice can increase blood concentration, so it is best to avoid grapefruit juice. Though this medication is generally safe based on clinical trials and post-marketing studies, rare serious side effects such as allergic reactions, skin rashes, and hepatitis may occur. Store this medication out of the reach of children and keep it in its original container. There is no specific antidote for overdose, so treatment should be provided based on symptoms, and liver function and muscle enzyme tests should be conducted.

Serious side effects

• Hives
• severe swelling (angioedema)
• chest tightness
• difficulty breathing
• cold sweat
• pallor
• severe rash with high fever
• blisters
• skin peeling
• pain in oral/ocular mucosa

Mild side effects

• Weakness
• malaise
• chest pain
• peripheral edema
• fatigue
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication can be sensitive to air or moisture, so it must be stored in a tightly closed container. The recommended storage temperature is between 1 and 30 degrees Celsius to ensure the medication's efficacy is maintained safely.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle