Aptostatin 20 mg (Atorvastatin Calcium Trihydrate)

Adult dose

For treating hyperlipidemia, the recommended initial dose is 10 mg once daily. For patients requiring further reduction in LDL cholesterol levels, an initial dose of 20 mg or 40 mg once daily may be started. The dosing should be individualized within the range of 10-80 mg once daily based on patient characteristics. Patients with homozygous familial hypercholesterolemia are prescribed 10-80 mg once daily.

Child dose

The recommended initial dose for pediatric patients (10-17 years) with heterozygous familial hypercholesterolemia is 10 mg once daily, with a maximum dose of 20 mg daily. Doses should be adjusted at intervals of 4 weeks or longer, according to treatment goals.

This medication may cause muscle-related symptoms; therefore, you should inform your doctor and stop the treatment immediately if you experience muscle pain or weakness, especially if severe. This medication can affect liver function, so it should not be used in individuals with liver disease or elevated liver function tests. Pregnant women, women who may become pregnant, and breastfeeding women should not take this medication. Children, especially those under 10 years of age, are advised against using this medication. This medication may interact with certain drugs; if you are taking other medications, be sure to inform your doctor or pharmacist. Patients who consume excessive alcohol or have a history of liver disease should use this medication cautiously and undergo regular liver function tests. During the treatment, if symptoms such as muscle pain, fatigue, or fever occur, consult healthcare professionals immediately. This medication may affect blood sugar levels, so patients at risk of diabetes should ensure thorough blood sugar management. Elderly patients are at increased risk for muscle abnormalities and other side effects, necessitating caution during treatment and regular health monitoring. It is advisable to avoid grapefruit juice while taking this medication, as it may increase serum concentration. Store this medication out of reach of children and in its original container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), severe body weakness, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination changes

Mild side effects

• Weakness
• fatigue
• chest pain
• peripheral edema
• tiredness
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a room temperature between 1 and 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle