Yunask Tablet 10 mg (Amlodipine Besylate)

Adult dose

Amlodipine is administered orally at a dose of 5 mg once daily, and may be increased up to a maximum of 10 mg daily based on patient response. Adjustments may be made appropriately according to age and symptoms.

This drug should not be used by certain patients. For instance, patients who have had allergic reactions to this drug or similar classes of drugs, nursing women, patients with severe liver dysfunction, patients with severe aortic stenosis, and patients in shock may be at risk if they take this medication. Moreover, special care is required for patients with very low blood pressure, those with severely impaired kidney function requiring dialysis, the elderly, and women who are pregnant or may become pregnant. Common side effects that may occur while taking this medication include flushing, fatigue, swelling, palpitations, dizziness, headaches, drowsiness, abdominal pain, and nausea. Rarely, more severe side effects such as hypotension, vasculitis, neurological abnormal symptoms, erectile dysfunction, dry mouth, dyspepsia, liver function abnormalities, and skin rash have been reported. Patients with heart failure or weakened liver function may experience intensified effects and side effects with this medication, hence caution is advised. The effects of this medication appear slowly, making it unsuitable for acute heart issues. Interactions can occur when this drug is taken in combination with several other medications. Specifically, taking it with grapefruit or grapefruit juice can enhance its effects, so it is recommended to avoid them. Caution is needed when taken with certain antibiotics, antihypertensives, and immunosuppressants, and it should be taken according to a doctor's guidance. For women who are pregnant or nursing, the safety of this drug is not confirmed; therefore, it should only be used upon a physician's judgment, and nursing should be discontinued during the course of treatment if applicable. It is recommended for children above 6 years of age, as safety and efficacy in children under 6 have not been established. In cases of overdose, serious symptoms may occur such as excessively low blood pressure or a rapid heartbeat, and immediate medical assistance should be sought. Measures like gastric lavage or reducing drug absorption may be necessary in the case of overdose, and close monitoring of blood pressure and cardiac function is required. Finally, this medication is known not to cause cancer or genetic problems even with long-term use, and it can be taken at regular dosage by the elderly.

Serious side effects

• Urticaria
• angioedema
• toxic epidermal necrolysis
• jaundice
• hepatitis
• severe edema
• severe allergic reactions
• liver abnormalities
• severe neurological symptoms
• severe skin adverse reactions

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly closed container to protect it from air and light exposure, and it is best kept at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the efficacy and safety of the drug.

Appearance

White, octagonal tablet

Package unit

30 tablets (10 tablets/PTP x 3)