Trispen Soft Capsules (Ibuprofen)

Adult dosage

Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, soft tissue injury, non-articular rheumatic diseases, acute gout, psoriatic arthritis: Administer orally 200-600mg once, 3-4 times a day. The maximum daily dose can be up to 3200mg. Mild to moderate pain, cold: Administer orally 200-400mg once, 3-4 times a day. Migraine: Administer 200-400mg orally, not exceeding 2 capsules within 24 hours.

Children's dosage

Juvenile idiopathic arthritis: Administer orally 30-40mg per kg of body weight divided into 3-4 doses daily. Adolescents aged 12 years and older: 200-400mg orally once, 3-4 times a day. For those weighing 30kg or more.

This medication may increase the risk of gastrointestinal bleeding in individuals who consume large amounts of alcohol daily, so consultation with a doctor or pharmacist is necessary. Individuals with cardiovascular disease or risk factors may experience cardiovascular adverse reactions when taking this medication long-term, therefore caution is required. It is advisable for those with a history of gastric ulcers or bleeding disorders, or gastrointestinal diseases, to avoid this medication. Those with severe liver, kidney, or heart dysfunction should refrain from taking this medication, and individuals allergic to any components of this medicine should also avoid it. When taking this medication, do not exceed the recommended dose and it is safer not to take it together with other non-steroidal anti-inflammatory drugs (NSAIDs). It should be avoided during the late stages of pregnancy as it may harm the fetus, and breastfeeding individuals should either cease nursing or stop taking the medication. Those with blood disorders, liver or kidney disease, heart disease, or hypertension must consult with healthcare professionals before taking this medication. There may be interactions with certain medications (for example, antihypertensives, lithium, anticoagulants, etc.) when taken concurrently, so caution is necessary. If severe allergic reactions, skin rashes, difficulty breathing, bleeding, severe abdominal pain, or abnormal liver function symptoms occur, stop taking the medication immediately and consult a healthcare professional. It is recommended to take this medication for the shortest duration possible at the minimal effective dose, and regular check-ups are required for long-term use. Patients with hypertension or heart failure should carefully monitor their blood pressure and fluid status during treatment with this medication. Usage of this medication after 20 weeks of pregnancy may affect the fetal kidney function, so if necessary, it should be used for the shortest period at the minimum dose, and regular ultrasound examinations should be conducted. Keep out of reach of children, and store in the original container tightly closed to prevent misuse and degradation of quality.

Serious side effects

• Hives, severe swelling (edema), chest tightness, breathing difficulties, cold sweat, pallor → severe allergic reaction
• Severe rashes, blisters, peeling skin, mucosal pain in mouth/eyes accompanying high fever → severe skin adverse reaction
• Shortness of breath or difficulty breathing, asthma attacks, cough + fever associated with breathing problems → respiratory issues
• Yellowing of skin or eyes (jaundice), extreme lethargy → liver issues (jaundice)

Mild side effects

• Nausea
• vomiting
• abdominal pain
• diarrhea
• headache
• dizziness
• drowsiness
• loss of appetite
• stomatitis
• thirst

Drug interactions

Do not take this medication with high-dose methotrexate. Also, do not take it with other non-steroidal anti-inflammatory drugs (NSAIDs). Consult with a physician or pharmacist when taken with low-dose aspirin, ACE inhibitors, lithium, furosemide and thiazide diuretics, low-dose methotrexate, coumarin anticoagulants (such as warfarin), and selective serotonin reuptake inhibitors.

This medication should be stored in a tightly closed container to prevent air or moisture from entering. The appropriate storage temperature is room temperature between 1 to 30 degrees Celsius.

Appearance

Transparent oval soft capsule containing a colorless to pale yellow transparent content

Package unit

10 Capsules/PTP