Medication info
Lepizol Tablets 5 mg (Aripiprazole)

Lepizol Tablets 5 mg (Aripiprazole)

Prescription medicationTablet경구
Ingredient · strength
Aripiprazole›5mg / 1 tablet
Manufacturer / importer
명인제약(주)
Appearance
Blue elongated tablet
Packaging
30 tablets/bottle, 200 tablets/bottle
Approval status
Active

MFDS item code 201108885 · Approved 2011.10.20 · Insurance code 651903570

Summary

Main use
Treatment of schizophrenia and bipolar disorder (acute mania, mixed episodes), adjunctive effect in major depressive disorder
Who takes it
Adults · Children
Adult dose
1. Schizophrenia - The recommended initial dosage is 10 mg or 15 mg once daily, regardless of food. - The dosage can be adjusted within a range of 10-30 mg per day, and increases should not be made before reaching a steady state in less than 2 weeks. - Maintenance therapy should be conducted at a dosage of 15 mg daily for at least 3 months. 2. Treatment of mania and mixed episodes associated with bipolar disorder -
Child dose
1. Schizophrenia in adolescents (13-17 years) - The recommended dosage is 10 mg daily, regardless of food. - The initial daily dosage is 2 mg, which is increased to 5 mg after 2 days, and to 10 mg after another 2 days.

Ingredients

Manufacturer
명인제약(주)

Efficacy & effects

Treatment of schizophrenia and bipolar disorder (acute mania, mixed episodes), adjunctive effect in major depressive disorder

  • Schizophrenia
  • acute mania associated with bipolar disorder
  • mixed episodes
  • major depressive disorder
  • irritability associated with autism spectrum disorder
  • Tourette's disorder
View approved original text

This medication is primarily used for the treatment of schizophrenia and acute mania and mixed episodes associated with bipolar disorder. It is also utilized as an adjunctive treatment for major depressive disorder and may help alleviate irritability associated with autism spectrum disorder. It is used for improving symptoms of Tourette's disorder. This medication is effective for various neuropsychiatric disorders and helps improve overall symptoms in patients.

How to take

Adult dose

1. Schizophrenia - The recommended initial dosage is 10 mg or 15 mg once daily, regardless of food. - The dosage can be adjusted within a range of 10-30 mg per day, and increases should not be made before reaching a steady state in less than 2 weeks. - Maintenance therapy should be conducted at a dosage of 15 mg daily for at least 3 months. 2. Treatment of mania and mixed episodes associated with bipolar disorder -

Child dose

1. Schizophrenia in adolescents (13-17 years) - The recommended dosage is 10 mg daily, regardless of food. - The initial daily dosage is 2 mg, which is increased to 5 mg after 2 days, and to 10 mg after another 2 days.

Precautions

This medication is primarily used for the treatment of psychiatric disorders. There is an increased risk of suicidal thoughts or behaviors when taking this medication, therefore close monitoring by a physician is necessary, especially for pediatric, adolescent, and young adult patients. During the initial treatment phase or when changing dosages, there may be an exacerbation of depression or abnormal changes in behavior, so careful observation is required. Family members or caregivers should closely monitor the patient's condition and immediately report any unusual signs to healthcare professionals. This medication cannot be used in patients with certain genetic lactose intolerance and should be used cautiously in patients at risk for cardiovascular diseases or hypotension. Additionally, this medication may increase the risk of seizures, so caution is necessary for patients with a history of epilepsy or a high risk of seizures. Common side effects of this medication may include drowsiness, dizziness, anxiety, insomnia, digestive disorders, and long-term use may lead to weight gain or movement disorders. In severe cases, life-threatening symptoms of neuroleptic malignant syndrome may occur, so if symptoms such as high fever, muscle rigidity, or mental changes appear, notify healthcare professionals immediately. For elderly patients with dementia, the risk of serious side effects such as stroke is increased, so the use of this medication is not recommended. Patients with diabetes should regularly check their blood sugar levels, and those at risk for thrombosis should also exercise caution. While taking this medication, avoid driving or operating dangerous machinery and consult a doctor immediately if any symptoms or side effects occur.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, paleness, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory distress with cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

  • Nausea
  • vomiting
  • constipation
  • headache
  • dizziness
  • akathisia
  • anxiety
  • insomnia
  • restlessness
  • drowsiness
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  • fatigue
  • increased appetite
  • rhinitis
  • weight gain
  • tremors
  • sedation
  • agitation
  • blurred vision
  • hypersalivation
  • myalgia
  • musculoskeletal stiffness
  • muscle spasms
  • abnormal muscle tone
  • lethargy
  • thirst
  • irritability
  • infections
  • upper respiratory infections
  • increased serum creatine phosphokinase
  • weight loss
  • increased serum prolactin
  • increased blood sugar
  • decreased appetite
  • hyperlipidemia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air or moisture ingress. The recommended storage temperature is between 1 to 30 degrees Celsius at room temperature. Proper storage will help maintain the efficacy of the medication.

Appearance and packaging

Appearance

Blue elongated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.