Mepiridem Tablet 2/500mg

Adult dose

This medication is administered 1 to 2 times a day before or during meals. The dosage can be adjusted based on each patient's current therapeutic regimen, efficacy, and tolerability, with appropriate blood sugar monitoring being essential. Treatment usually starts with a low dose, and adjustments are made based on the patient's current medications and blood sugar levels. In clinical trials, the initial total daily dose was 2 mg of Glymeperide/Metformin Hydrochloride.

This medication should not be administered to patients with significantly reduced kidney function due to the risk of severe lactic acidosis or hypoglycemia. In particular, if experiencing dehydration or taking medications that may affect kidney function, administration of this medication should be temporarily stopped and a consultation with a physician is required. Patients at risk for cardiovascular diseases must exercise caution before and after using this medication and carefully consider the benefits and risks. This medication is not to be used in patients with insulin-dependent diabetes, severe liver or kidney dysfunction, pregnant or nursing women. Additionally, the administration of this medication should be halted before and after examinations using radiologic contrast agents and can be resumed only after kidney function has stabilized. Patients at high risk for hypoglycemia, those with poor nutritional status or irregular eating patterns, the elderly, and those with liver dysfunction should use this medication with caution. This medication can cause gastrointestinal symptoms, allergic reactions, hematological abnormalities, and vitamin B12 deficiency, so patients should inform their doctor immediately of any adverse symptoms. Blood sugar control and kidney function should be routinely monitored, with particular attention given to the elderly or those with reduced kidney function. There may be interactions when used in combination with other medications, so all medications being taken should be disclosed to healthcare providers, and caution is required with sudden changes in medications. Pregnant or nursing women should avoid this medication and may need to switch to insulin therapy if necessary. Safety in children has not been established, so it should be administered cautiously to children. In cases of overdose, severe hypoglycemia or lactic acidosis may occur, requiring immediate medical attention for proper treatment. Caution is needed when driving or operating machinery as hypoglycemia or impairment of agility may occur. This medication should be kept out of reach of children and stored in its original container to maintain quality.

Serious side effects

• Urticaria
• severe swelling (edema)
• difficulty breathing
• hypotension
• severe allergic reactions
• liver dysfunction (jaundice)
• acute renal failure
• lactic acidosis
• severe hypoglycemia
• thrombocytopenic purpura

Mild side effects

Diarrhea, nausea, vomiting, abdominal distension, loss of appetite, dyspepsia, constipation, abdominal pain, metallic taste, visual impairment, nausea, feeling of fullness or pressure in the upper abdomen, abdominal pain, diarrhea, erythema, itching, rash, taste disturbance, thrombocytopenia, leukopenia, hemolytic anemia, erythropenia, agranulocytosis, pancytopenia, vitamin B12 decrease, increase in liver enzymes, liver dysfunction, hepatitis, allergic vasculitis, skin reactions.

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. The storage temperature should be maintained between 1 and 30 degrees Celsius. Proper storage will help retain the drug's efficacy over a long period.

Appearance

White rectangular film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle