Medication info
Wingliem Tablets 1/250 mg

Wingliem Tablets 1/250 mg

Prescription medicationTablet경구
Ingredient · strength
Glimepiride›1mg / 1 tabletMetformin Hydrochloride›250mg / 1 tablet
Manufacturer / importer
한화제약(주)
Appearance
White, oblong, film-coated tablet
Packaging
30 tablets/box [(10 tablets/PTP X 3)]
Approval status
Active

MFDS item code 201107290 · Approved 2011.09.29 · Insurance code 651601510

Summary

Main use
Improved blood sugar control in type 2 diabetes
Who takes it
Adults
Adult dose
This medication is administered 1 to 2 times a day before meals or with meals. Dosage can be adjusted based on each patient's current treatment regimen, effectiveness, and tolerance, and appropriate blood sugar monitoring should be conducted. Treatment is typically initiated at a low dose, and the dosage can be adjusted based on the patient's current medication and blood sugar levels. In clinical trials, the initial daily dose was glymepiride/metformin hydrochloride 2 mg/500 mg.

Ingredients

Manufacturer
한화제약(주)

Efficacy & effects

Improved blood sugar control in type 2 diabetes

View approved original text

This medication contains two components, glymepiride and metformin, to help control blood sugar levels in patients with type 2 diabetes. It is used in conjunction with dietary management and exercise therapy to effectively improve blood sugar levels. If taken continuously, it can have a positive effect on blood sugar management.

How to take

Adult dose

This medication is administered 1 to 2 times a day before meals or with meals. Dosage can be adjusted based on each patient's current treatment regimen, effectiveness, and tolerance, and appropriate blood sugar monitoring should be conducted. Treatment is typically initiated at a low dose, and the dosage can be adjusted based on the patient's current medication and blood sugar levels. In clinical trials, the initial daily dose was glymepiride/metformin hydrochloride 2 mg/500 mg.

Precautions

This medication carries a risk of severe lactic acidosis or hypoglycemia, so dosage should be discontinued and a physician consulted if there is a sudden decline in kidney function or signs of dehydration. This medication should not be used in patients with severely impaired renal function, severely impaired liver function, or those who are pregnant or breastfeeding. Patients who are at high risk for hypoglycemia, such as the elderly, malnourished individuals, those who eat irregularly, or those engaged in vigorous exercise, should use caution when taking this medication. At the beginning of treatment, gastrointestinal symptoms (such as diarrhea, nausea, and vomiting) may occur, but they are generally temporary and may be relieved by taking the medication with food. This medication lowers blood sugar, so patients should be aware of hypoglycemic symptoms and promptly consume sugar when symptoms occur, seeking medical help if necessary. If renal function is impaired, the drug can accumulate in the body, increasing the risk of side effects, thus regular kidney function tests are necessary, and dosage adjustments or discontinuation may be required based on the condition. This medication can interact with other drugs, so patients should inform their healthcare provider if they are taking other medications and should also exercise caution when starting or stopping new medications. Alcohol consumption may increase the risk of side effects from this medication, so patients should avoid excessive drinking. Women who are pregnant or planning to become pregnant are advised to use insulin therapy instead of this medication, and it is also recommended to avoid its use while breastfeeding. Safety in children and adolescents has not been adequately established, so special caution is required when used in this population. Patients taking this medication should regularly monitor their blood sugar, undergo blood tests, and have kidney function tests to assess treatment effectiveness and check for side effects. In case of overdose, severe hypoglycemia or lactic acidosis can occur, so patients should strictly adhere to the prescribed dosage and contact healthcare providers immediately if abnormal symptoms appear. Caution is needed when driving or operating machinery due to the possibility of decreased attention from hypoglycemia. This medication should be stored out of reach of children, and care should be taken to avoid transferring it to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), difficulty breathing, severe allergic reactions, jaundice, liver damage, hepatitis, severe neurological symptoms (headache, seizures, confusion, visual disturbances, paralysis), severe edema, thrombocytopenia, leukopenia, hemolytic anemia, erythrocytopenia, granulocytopenia, agranulocytosis, pancytopenia, severe hypoglycemic symptoms (headache, trembling, paralysis, coma, loss of consciousness, etc.), lactic acidosis, hypoglycemia,

Mild side effects

  • Nausea
  • vomiting
  • abdominal distension
  • loss of appetite
  • indigestion
  • constipation
  • abdominal pain
  • discomfort
  • metallic taste
  • visual impairment
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  • erythema
  • itching
  • rash
  • diarrhea
  • nausea
  • leg edema
  • dizziness
  • palpitations
  • indigestion
  • hair loss
  • weight gain
  • decreased serum sodium concentration
  • hypothyroidism
  • magnesium deficiency during diarrhea
  • encephalopathy
  • prostatic hyperplasia
  • erectile dysfunction
  • facial flushing
  • gastritis
  • joint pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be kept in a well-closed container to prevent air or moisture from entering, and it is best stored at a temperature between 1 to 30 degrees Celsius. By storing it this way, the effectiveness of the medication can be maintained and deterioration can be prevented.

Appearance and packaging

Appearance

White, oblong, film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP X 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.