AjuBron Tablet 12.5 mg (Tianeptine Sodium)

Adult dose

○ Adults : Administer 12.5 mg of tianeptine sodium orally per dose, 3 times daily before meals. ○ Limit the dose to twice daily in elderly patients aged 70 years or older or patients with renal failure. ○ Adjust the dose appropriately according to symptoms. ○ Abrupt discontinuation of treatment should be avoided. To reduce the risk of withdrawal reactions, gradually reduce the dose over 7 ~ 14 days. (See “General precautions” under Precautions for use.)

This medication is used for the treatment of depression and may pose a risk of suicidal thoughts or self-harming behavior, so patients should be closely monitored for several weeks after starting treatment. Particularly, patients with a history of suicide attempts or suicidal thoughts require more careful observation. This drug should not be used in children under 15 years of age or in patients with certain genetic disorders, and those taking MAO inhibitors. During treatment, various side effects such as loss of appetite, insomnia, drowsiness, headaches, palpitations, and gastrointestinal issues may occur, so if any abnormal symptoms arise, immediate consultation with a doctor is recommended. Patients who are about to undergo surgery should inform the anesthesiologist about the use of this medication, and may need to discontinue it before surgery if necessary. It is advisable to avoid taking this medication with alcohol, as it can be dangerous. Abrupt discontinuation of this drug may lead to withdrawal symptoms such as anxiety, muscle pain, and insomnia, so the dosage should be gradually reduced according to the doctor's instructions. Caution is advised when driving or operating machinery as drowsiness may occur. Patients with impaired kidney function or those aged 70 and older should limit their dosage, and attention should be paid to electrolyte imbalances such as hyponatremia. In case of overdose, decreased consciousness or coma may occur, and immediate medical treatment should be sought. Keep out of reach of children and do not transfer to another container for safety.

• Loss of appetite
• hyponatremia
• nightmares
• drug abuse and dependence
• suicidal thoughts
• suicidal behavior
• confusion
• hallucinations
• insomnia
• drowsiness

This medication should be stored in a tightly closed container to prevent air and moisture from entering. It is recommended to maintain the storage temperature between 1 and 30 degrees Celsius.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle