Stiarone Tablet (Tianepine Sodium)

Adult dose

○ Adults : Administer 12.5 mg of tianeptine sodium orally per dose, 3 times daily before meals. ○ Limit the dose to twice daily in elderly patients aged 70 years or older or patients with renal failure. ○ Adjust the dose appropriately according to symptoms. ○ Abrupt discontinuation of treatment should be avoided. To reduce the risk of withdrawal reactions, gradually reduce the dose over 7 ~ 14 days. (See “General precautions” under Precautions for use.)

This medication is used for the treatment of depression, but the risk of suicidal thoughts or self-harm may increase in the early stages of treatment, so patients should be monitored closely. Special attention should be given to those with a history of suicide attempts or suicidal thoughts. This medication should not be administered to children under 15 years old or patients with certain genetic disorders, and caution is needed when used in conjunction with specific medications, as it may pose risks. Various side effects such as reduced appetite, insomnia, drowsiness, headaches, palpitations, and gastrointestinal disturbances may occur during treatment, so if any abnormal symptoms occur, consult a doctor immediately. Patients undergoing surgery must inform the anesthesiologist about this medication, and the drug may need to be discontinued for a certain period before surgery. Co-administration with alcohol should be avoided, and sudden discontinuation of the medication may lead to withdrawal symptoms such as anxiety or muscle pain, so the dosage should be gradually reduced according to a doctor's instructions. Caution is advised when driving or operating machinery due to the possibility of drowsiness, and patients with a history of alcohol or drug dependence should be cautious of drug abuse. Patients with impaired kidney function or elderly patients may need dosage adjustments, and regular tests are required as there is also a risk of electrolyte imbalances such as hyponatremia. In case of overdose, drowsiness or coma may occur, so immediate medical attention must be sought. This medication should be stored out of the reach of children and should not be transferred to other containers for safety.

• Loss of appetite
• hyponatremia
• nightmares
• drug abuse and dependence
• suicidal ideation
• suicidal behavior
• confusion
• hallucinations
• insomnia
• drowsiness

This medication should be stored at room temperature between 1°C and 30°C, and it is important to keep it in a tightly sealed container to prevent air or moisture from entering.

Appearance

White oval-shaped coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle