Neptin Tablets 12.5 Milligrams (Thianephtine Sodium)

Adult dose

○ Adults : Administer 12.5 mg of tianeptine sodium orally per dose, 3 times daily before meals. ○ Limit the dose to twice daily in elderly patients aged 70 years or older or patients with renal failure. ○ Adjust the dose appropriately according to symptoms. ○ Abrupt discontinuation of treatment should be avoided. To reduce the risk of withdrawal reactions, gradually reduce the dose over 7 ~ 14 days. (See “General precautions” under Precautions for use.)

This medication is used for the treatment of depression and may increase the risk of suicidal thoughts or self-harm behaviors, so patients should be closely monitored for several weeks after starting treatment. Special care is needed for patients with a history of suicide attempts or suicidal thoughts. This medication should not be used in children under 15 years of age, patients with certain genetic disorders, or patients taking MAO inhibitors due to the potential for severe side effects caused by drug interactions. During the use of this medication, various side effects such as loss of appetite, insomnia, drowsiness, headache, muscle pain, indigestion, and skin rash may occur, so if any abnormal symptoms appear, consultation with medical personnel should be sought immediately. Patients about to undergo surgery should inform the anesthesiologist about this medication and may need to discontinue it for a period before surgery; it is also advisable not to take it alongside alcoholic beverages or medications containing alcohol. Sudden discontinuation of the medication may lead to withdrawal symptoms such as anxiety, muscle pain, and insomnia, so it should be tapered off gradually according to the doctor's instructions. Caution should be exercised since drowsiness or decreased concentration may occur while driving or operating machinery, and patients with a history of drug or alcohol dependence need to be mindful of potential substance misuse. Patients with impaired kidney function or those over 70 years of age may require limitations on the dosage to twice a day due to prolonged half-life of the medication. In case of overdose, symptoms such as drowsiness or coma may occur, and immediate emergency treatment should be sought. The medication should be stored safely out of reach of children.

• Loss of appetite
• hyponatremia
• nightmares
• drug abuse and dependence
• suicidal thoughts
• suicidal behavior
• confusion
• hallucinations
• insomnia
• drowsiness

This medication should be stored at room temperature between 1 to 30 degrees Celsius, and it is important to keep it in a tightly sealed container to prevent air exposure. This helps maintain the medication's effectiveness and prevent degradation.

Appearance

White oval tablet

Package unit

1 bottle/box (30 tablets/bottle), 1 bottle/box (300 tablets/bottle)