Celecoxib Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient and may be administered regardless of meals. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg daily may be administered. If no effect is observed after 6 weeks of treatment with 400 mg daily, other treatment options should be considered. Acute pain and primary dysmenorrhea: The initial recommended dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be discussed with a doctor or pharmacist before use for those who regularly consume more than three alcoholic drinks per day. Taking this medication while drinking can increase the risk of gastrointestinal bleeding. This drug may increase the risk of cardiovascular diseases. There is a possibility of serious cardiovascular problems such as myocardial infarction or stroke, therefore it should be used at the minimum effective dose and for the shortest duration possible. If cardiovascular symptoms appear, immediate medical attention is required. This medication may result in serious problems such as gastrointestinal perforation, ulceration, or bleeding. Caution is especially important for the elderly or for those with a history of gastrointestinal issues. If symptoms such as epigastric pain, indigestion, black stools, or vomiting blood occur, seek immediate treatment. This medication should not be administered to individuals with specific allergies or diseases. For example, individuals with allergies to this medication's components or to sulfonamides, severe liver or kidney dysfunction, active peptic ulcer, inflammatory bowel disease patients, those with heart disease, pregnant women, or nursing mothers should not take this medication. Special caution is required for individuals with poor liver or kidney function or for those with asthma, heart failure, hypertension, edema, blood coagulation disorders, or diabetes. They should use this medication cautiously and consult their doctor. This medication may have various side effects. Symptoms such as indigestion, diarrhea, headache, dizziness, hypertension, skin rash, liver dysfunction, kidney dysfunction, cardiovascular issues, and others may occur, so if any abnormal symptoms arise, consult a healthcare professional immediately. This medication may interact with other drugs, therefore if you are currently taking any medications, it is crucial to inform your doctor or pharmacist. Attention is needed when taken with medications metabolized in the liver, antihypertensives, anticoagulants, diuretics, or antidepressants. Pregnant women or those who may become pregnant, as well as nursing mothers, should not take this medication and should cease use immediately if pregnancy occurs during treatment. The safety and efficacy of this medication have not been established for children or adolescents under 18 years of age, and it is advisable not to use it. Elderly patients may have reduced kidney and liver function, thus they should use this medication more cautiously and dosage adjustments may be necessary. If this medication is taken over a prolonged period, regular blood tests and liver and kidney function evaluations should be conducted to monitor for abnormalities. In case of overdose, symptoms such as lethargy, drowsiness, nausea, vomiting, and abdominal pain may occur, and appropriate treatment should be sought immediately. This medication should be kept out of the reach of children, and transferring it to another container may negatively affect the quality.

Gastrointestinal bleeding, cardiovascular thrombotic reaction, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, frequent urination, kidney stones, urinary incontinence, urinary tract infection, visual disturbances, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, anorexia, increased LDH, hypoglycemia, hyponatremia, synovial sac, arthralgia, arthritis, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various body parts, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, injection site reaction, skin nodules, headache, leg cramps, sensory loss, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, angioedema, anorexia, increased appetite, depression, neuropsychological reactions, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory infection, shingles, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, chest neoplasm, chest pain, menstrual pain, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urinary urobilinogen, cholelithiasis, hepatitis, jaundice, hepatic failure, fulminant hepatitis, hepatic necrosis, vasculitis, pulmonary embolism, interstitial pneumonia, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease glomerulonephritis, female infertility

This medication should be stored in a tightly sealed container to protect from air and moisture, and the temperature should be maintained between 15 and 30 degrees Celsius. Proper storage will help maintain the medication's efficacy over time.

Appearance

White to off-white powder filled in white capsules with yellow banding on top and bottom

Package unit

30 capsules/bottle, 100 capsules/bottle