Langaton Capsule 30 mg (Lansoprazole)

Adult dose

This medication should be taken before meals. 1. Short-term treatment of active duodenal ulcers: Administer Lansoprazole 15 mg orally once daily for 4 weeks. 2. Short-term treatment of active benign gastric ulcers: Administer Lansoprazole 30 mg orally once daily for 8 weeks. 3. Eradication of Helicobacter pylori to prevent recurrence of duodenal ulcer: 1) Administer Lansoprazole 30 mg with Clarithromycin 250-500 mg and Amoxicillin 1,000 mg twice daily (every 12 hours) for 7 days, may extend to 14 days if necessary. 2) Administer Lansoprazole 30 mg with Amoxicillin 1,000 mg three times daily (every 8 hours) for 14 days. 4. Maintenance therapy after treatment of duodenal ulcers: Administer Lansoprazole 15 mg orally once daily. The duration of comparative clinical trials did not exceed 12 months. 5. Treatment of NSAID-induced gastric ulcers: Administer Lansoprazole 30 mg orally once daily for 8 weeks. The duration of comparative clinical trials did not exceed 8 weeks. 6. Reduction of the risk of NSAID-induced gastric ulcers: Administer Lansoprazole 15 mg orally once daily for 12 weeks. The duration of comparative clinical trials did not exceed 12 weeks. 7. Short-term treatment of symptoms related to gastroesophageal reflux disease: Administer Lansoprazole 15 mg orally once daily for 8 weeks. 8. Short-term treatment of erosive esophagitis: Administer Lansoprazole 30 mg orally once daily for 8 weeks. 9. Maintenance therapy after treatment of erosive esophagitis: Administer Lansoprazole 15 mg orally once daily. 10. Pathological hypersecretion conditions including Zollinger-Ellison syndrome: Dosage of Lansoprazole for pathological hypersecretion conditions varies by patient. Typically start with 60 mg orally once daily. The dose should be adjusted according to the patient’s needs and may be continued as long as clinically effective. Doses up to 90 mg orally twice daily have been used. If the daily dose exceeds 120 mg, it should be divided into multiple doses. Children and Adolescents (12 to 17 years) 1. Short-term treatment of symptoms related to non-erosive gastroesophageal reflux disease: 15 mg once daily for 8 weeks. 2. Short-term treatment of erosive esophagitis: 30 mg once daily for 8 weeks. Children (1 to 11 years) Short-term treatment of symptoms related to gastroesophageal reflux disease and erosive esophagitis: Under 30 kg: 15 mg once daily for 12 weeks. Over 30 kg: 30 mg once daily for 12 weeks. Elderly patients Dosage adjustments are needed as clearance may decrease in the elderly. Do not exceed 30 mg per day.

Child dose

Children and Adolescents (12 to 17 years): 1. Short-term treatment of symptoms related to non-erosive gastroesophageal reflux disease: 15 mg once daily for 8 weeks. 2. Short-term treatment of erosive esophagitis: 30 mg once daily.

This medication should not be used in patients who are allergic to any of its components or to benzimidazole derivatives. It is also advisable not to administer it to individuals with hypersensitivity to penicillin or macrolide antibiotics. Pregnant patients or those with genetic issues such as lactose intolerance are recommended to avoid this medicine. Care should be taken when administering to patients with a history of drug allergies, poor liver function, elderly individuals, nursing mothers, and children. While rare, serious side effects including anaphylaxis, blood disorders, liver dysfunction, and severe skin reactions may occur during use; if any such symptoms appear, the medication should be discontinued immediately, and medical attention should be sought. As this drug suppresses gastric acid secretion, it may interact with other medications. Caution is especially needed when co-administering with HIV therapies or certain antibiotics and anticoagulants, and adjustment or monitoring of drug intervals may be required. Prolonged use may lead to vitamin B12 deficiency or hypomagnesemia; regular check-ups are recommended. Additionally, the risk of fractures may increase, thus caution is necessary with long-term use. Dizziness, drowsiness, or vision disturbances may occur during use; exercise caution when driving or operating machinery. Pregnant or nursing women should refrain from using this drug, and if it is essential, professional consultation is necessary. In cases of overdose, immediate emergency treatment and symptomatic care are required as it cannot be eliminated by hemodialysis.

Serious side effects

Hives, severe swelling (angioedema), tightness in the chest, shortness of breath (dyspnea, asthma attacks), cold sweat, paleness, anaphylaxis, anaphylactic shock, angioedema, bronchospasm, acute interstitial nephritis, shock, pancytopenia, agranulocytosis, hemolytic anemia, granulocytopenia, thrombocytopenia, anemia, jaundice (yellowing of the skin or eyes), liver dysfunction accompanied by elevations in AST/ALT, toxic epidermal necrolysis (TEN).

Mild side effects

• Headache
• diarrhea
• altered taste
• abdominal pain
• nausea
• vomiting
• constipation
• dizziness
• drowsiness
• insomnia

This medication should be stored in a sealed container to protect it from air and moisture, and it is safe to keep it at a temperature between 1°C and 30°C. Storing it this way helps maintain the medication's effectiveness and prevents deterioration.

Appearance

A hard capsule filled with white granules that are white to light brown, with a green upper part and a white lower part.

Package unit

30 capsules [10 capsules/PTP (PVDC)x3]