Celebrex Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient and may be administered regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily or 100 mg per dose twice daily. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg per dose twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily or 100 mg per dose twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg daily may be administered. If no effect is observed after 6 weeks of treatment with 400 mg daily, consider another treatment method. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of administration if needed. From the second day of administration, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment : For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may pose a risk of gastric bleeding when taken by individuals who consume a lot of alcohol daily, so it is essential to consult with a doctor or pharmacist. People with heart or vascular problems or risk factors may develop cardiovascular issues such as myocardial infarction or stroke while using this medication, so it should be used at the minimal effective dose and duration. Individuals with ulcers or bleeding in the stomach should be cautious as taking this medication may lead to serious problems such as gastrointestinal perforation, ulcers, and bleeding. Those who have had allergic reactions to this medication or have a history of allergies to sulfonamides, aspirin, or other non-steroidal anti-inflammatory drugs should not take this medication. Patients with severe liver or kidney dysfunction, heart failure, active peptic ulcer, inflammatory bowel disease, pregnant women, and nursing mothers should not take this medication. Those with mild liver or kidney dysfunction, asthma, hypertension, heart failure, or fluid retention should use this medication cautiously and follow the doctor's instructions. This medication may cause various side effects including dyspepsia, headache, dizziness, hypertension, edema, skin rash, abnormal liver function, etc., so any unusual symptoms should be reported to a doctor immediately. This medication has numerous interactions with other drugs, and caution is needed when taken with medications that affect metabolism in the liver, antihypertensives, anticoagulants, diuretics, etc. It's crucial to inform the doctor of any current medications being taken. Pregnant women or those planning to become pregnant should not take this medication, and it is advisable to avoid it while nursing as well. This medication is not recommended for use in children and adolescents under 18 years old as its safety and effectiveness have not been established. Elderly patients may have a higher likelihood of liver, kidney, and heart function impairment, so particular caution is needed when administering this medication, and dosage should be adjusted if necessary. For long-term use of this medication, regular blood tests and examinations of liver and kidney function should be conducted to check for abnormalities. In case of overdose, symptoms such as lethargy, drowsiness, nausea, vomiting, and abdominal pain may occur, and immediate hospital treatment is required. This medication should be stored out of the reach of children and should not be transferred to other containers for safety.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, upper and lower gastrointestinal tract perforation, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, indigestion, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, bowel perforation, pancreatitis, elevated liver enzymes, itching, rash, hives, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, frequent urination, kidney stones, urinary incontinence, urinary tract infections, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute kidney injury, interstitial nephritis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthritis, skeletal abnormalities, myalgia, cervical tension syndrome, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various areas, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, injection site reactions, skin nodules, headache, leg cramps, tension hypertension, sensory loss, migraine, neuralgia, neuropathy, sensory abnormality, cerebral infarction, aseptic meningitis, ataxia, suicidal thoughts, loss of smell, loss of taste, worsening of allergies, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reaction, angioedema, insomnia, loss of appetite, increased appetite, depression, neuro-reactivity, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory tract infections, shingles, wound infections, gingivitis, herpes simplex, herpes zoster, bacterial infections, fungal infections, soft tissue infections, viral infections, candidiasis, genital candidiasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic changes of the breast, thoracic neoplasm, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostatic disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, increased ALT, increased AST, increased γ-GTP, increased ALP, positive urinary urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, acute hepatitis, liver necrosis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute kidney injury, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis, female infertility, chest pain, anaphylactic reaction, hallucinations, cerebral hemorrhage

This medication should be stored in a sealed container to prevent air or moisture from entering, and it is best kept at room temperature between 15 to 30 degrees Celsius. Proper storage will help maintain the efficacy of the medication for a longer period.

Appearance

A hard capsule filled with white to light yellow powder, with white upper and lower parts.

Package unit

30 capsules per bottle