Medication info

Multibic 2 Potassium Solution 5L

Prescription medication주사
Ingredient · strength
Potassium Chloride›2.982gCalcium Chloride Hydrate›4.41gMagnesium Chloride Hexahydrate›2.033gGlucose Hydrate›22gSodium Chloride›6.453gSodium Bicarbonate›3.104gSodium›Strength being verifiedPotassium›Strength being verifiedCalcium›Strength being verifiedMagnesium›Strength being verifiedChlorine›Strength being verifiedHydrocarbonate›Strength being verifiedGlucose›Strength being verified
Manufacturer / importer
(주)프레제니우스메디칼케어코리아
Appearance
Colorless and transparent liquid formulation contained in a clear plastic bag
Packaging
200 bags/box [5,000 mL per bag]
Approval status
Active

MFDS item code 201103797 · Notified 2011.06.14 · Insurance code 664300581

Summary

Main use
Effect of fluid replacement and dialysis solution use in patients with acute renal failure and intoxication
Who receives it
Adults
Adult administration
1) In cases of acute renal failure, a dosage of 2,000 mL/h based on a 70 kg adult is appropriate for waste removal, depending on the patient's metabolic level. The dosage should be adjusted according to the patient's body weight. 2) The dosage and duration for blood dialysis, hemofiltration, and dialysis filtration needed for treating acute intoxication symptoms should be determined based on toxin concentration and clinical severity. 3) The maximum recommended dosage is 75 L per day.

Ingredients

Importer
(주)프레제니우스메디칼케어코리아

Efficacy & effects

Effect of fluid replacement and dialysis solution use in patients with acute renal failure and intoxication

  • Acute renal failure
  • acute intoxication
  • hyperkalemia
View approved original text

This medication is used as a fluid replacement or dialysis solution when continuous renal replacement therapy is required in patients with acute renal failure. It is also applicable to patients with acute intoxication caused by water-soluble toxins that can be removed by filtration or dialysis. It is particularly effective in patients at risk of hyperkalemia. In other words, this medication helps to remove toxins and excess potassium from the bloodstream in cases where kidney function is impaired and blood filtration and dialysis treatment are necessary. This helps to maintain the patient's electrolyte balance and stabilize their condition.

How it is given

Adult administration

1) In cases of acute renal failure, a dosage of 2,000 mL/h based on a 70 kg adult is appropriate for waste removal, depending on the patient's metabolic level. The dosage should be adjusted according to the patient's body weight. 2) The dosage and duration for blood dialysis, hemofiltration, and dialysis filtration needed for treating acute intoxication symptoms should be determined based on toxin concentration and clinical severity. 3) The maximum recommended dosage is 75 L per day.

Precautions

This medication should not be used in certain patients. It should not be administered to patients who are allergic to any of its components, have low potassium levels, metabolic alkalosis with high blood acidity, or patients with excessive metabolism or inadequate blood supply, and those at high risk of bleeding. Gastrointestinal issues such as nausea or vomiting, blood pressure changes, muscle cramps, fluid imbalance, and electrolyte abnormalities may occur with this medication. Additionally, if there is either excess or insufficient fluid, symptoms such as shortness of breath, leg swelling, dizziness, and thirst may appear. While using this medication, potassium, sodium, calcium, magnesium, phosphate, and glucose levels in the blood should be frequently monitored, and fluid status must be observed carefully. If hypokalemia or hyperkalemia occurs, appropriate measures are required. Furthermore, this medication may not adequately supplement certain essential nutrients during hemodialysis or hemofiltration; if needed, nutritional supplementation may be required. Care should be taken for interactions when used with other medications, particularly with cardiac medications such as digitalis which may increase toxicity. Caution is also advised when taking vitamin D or calcium-containing preparations, as calcium levels may become excessively high. Pregnant or nursing women are advised against using this medication, and it is also not recommended for children as safety has not been adequately established. In the event of overdose, severe fluid and electrolyte imbalances may occur, which could lead to heart or lung problems, so immediate consultation with medical personnel is necessary. This medication must be mixed before use, heated to a temperature similar to body temperature, and the solution should be frequently checked for precipitates. If precipitation is found, the solution and tubing must be replaced promptly, and the patient should be carefully monitored. When stored, the mixed solution should be used within 48 hours at or below 30 degrees Celsius, and it is recommended to administer it immediately after use. This medication is known not to affect driving or machine operation abilities.

Side effects and when to seek care immediately

Serious side effects

Shortness of breath, ankle and leg swelling, congestive heart failure and/or pulmonary congestion

Mild side effects

Nausea, vomiting, hypotension, hypertension, muscle cramps, fluid overload, dehydration, electrolyte imbalances (such as hypokalemia), hypophosphatemia, hyperglycemia, metabolic alkalosis, hematological abnormalities (abnormal serum concentrations), dizziness, thirst, blood pressure changes, heart rate changes, changes in pulmonary arterial pressure, calcium carbonate precipitation observed.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in sealed containers to avoid air exposure, in a cool place between 4 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness and prevent deterioration.

Appearance and packaging

Appearance

Colorless and transparent liquid formulation contained in a clear plastic bag

Package unit

200 bags/box [5,000 mL per bag]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.