Tiarone Tablets (Tianeptine Sodium)

Adult dose

○ Adults : Administer tianeptine sodium 12.5 mg orally 3 times daily before meals. ○ Limit administration to 2 times daily in elderly patients aged 70 years or older or patients with renal impairment. ○ Adjust the dose as appropriate according to symptoms. ○ Avoid abrupt discontinuation of treatment. To reduce the risk of withdrawal reactions, gradually taper the dose over 7 ~ 14 days. (See “General precautions” under Precautions for use.)

This medication is used to treat depression, and during the initial treatment period, suicidal thoughts or behaviors may worsen, so patients should be closely monitored. Particularly, extra caution is needed for patients with a history of suicide attempts or thoughts. It should not be administered to children under 15 years of age, patients with certain genetic disorders, or those taking MAO inhibitors. While taking this medication, various side effects such as decreased appetite, nightmares, insomnia, dizziness, palpitations, abdominal pain, and myalgia may occur, so symptoms should be carefully observed. Patients scheduled for surgery should inform the medical staff about the use of this medication in advance, and may need to discontinue it 24-48 hours before surgery if necessary. Avoid taking it with alcohol or certain psychiatric medications, and do not stop taking the medication abruptly; it should be gradually reduced according to a doctor's instructions. Additionally, this drug may cause drowsiness or decreased alertness, so caution is needed when driving or operating machinery. Elderly patients or those with impaired kidney function should have their dosage adjusted, and caution is required for electrolyte imbalances such as hyponatremia. It is advisable to avoid use during pregnancy, and breastfeeding mothers should also refrain from taking it. In case of overdose, symptoms such as drowsiness and coma may occur, requiring immediate medical treatment. Keep out of reach of children, and do not transfer the medication to another container.

• Loss of appetite
• hyponatremia
• nightmares
• drug abuse and dependence
• suicidal thoughts
• suicidal behavior
• confusion
• hallucination
• insomnia
• drowsiness

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius to preserve the efficacy and safety of the medication over time.

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle