Stiarone Tablet (Tianepine Sodium)

Adult dose

○ Adults : Administer 12.5 mg of tianeptine sodium orally before meals 3 times daily. ○ For elderly patients aged 70 years or older or patients with renal impairment, limit administration to 2 times daily. ○ Adjust the dose as appropriate according to symptoms. ○ Abrupt discontinuation of treatment should be avoided. To reduce the risk of withdrawal reactions, the dose should be gradually reduced over 7 ~ 14 days. (See “General Precautions” under Precautions for Use.)

This medication is used for the treatment of depression, and during the initial stages of treatment, suicidal thoughts or behaviors may become more pronounced, so patients should be carefully monitored. Particularly, patients at high risk of suicide or young patients under the age of 25 require more diligent observation. This medication should not be used in children under 15 years old, in patients with certain genetic disorders, and in patients taking certain drugs. During treatment, side effects such as decreased appetite, insomnia, drowsiness, headache, digestive issues, skin rash, etc., may occur, so if unusual symptoms appear, consult a doctor immediately. Before surgery, be sure to inform healthcare providers that you are taking this medication, and stop it if necessary; avoid taking with alcohol. Do not abruptly discontinue this medication, and when stopping, gradually taper off under a doctor's guidance to prevent withdrawal symptoms. Caution is required when driving or operating machinery, as drowsiness or decreased concentration may occur. Patients with poor kidney function or the elderly may require dosage adjustments, and one should be cautious as electrolyte imbalances such as hyponatremia may occur. It is advisable for pregnant or nursing women to avoid using this medication. In case of overdose, loss of consciousness or coma may occur, so seek appropriate medical treatment immediately. Store this medication out of reach of children, and do not transfer it to other containers for safety.

• Loss of appetite
• hyponatremia
• nightmares
• drug abuse and dependence
• suicidal thoughts
• suicidal behavior
• confusion
• hallucinations
• insomnia
• drowsiness

This medication should be stored in a tightly sealed container to protect it from air and moisture, preferably at room temperature between 1°C and 30°C. Proper storage will help maintain the effectiveness of the medication for a longer period.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle