Pitavacare Tablets 2mg (Pitavastatin Calcium)

Adult dose

For adults, the usual dose of Pitavastatin Calcium is 1 to 2 mg once daily. If the LDL cholesterol-lowering effect is insufficient, the dose may be increased to a maximum of 4 mg per day. The dosage should be adjusted based on the patient's response at intervals of 4 weeks or more.

This medication is used for the treatment of hypercholesterolemia and is mainly metabolized by the liver. Patients with hypersensitivity to any component of this medication, those with active liver disease, severe hepatic impairment, and pregnant or nursing women should not use this medication. Additionally, this medication contains lactose and should not be administered to patients with genetic metabolic disorders such as galactose intolerance. Patients with impaired renal function or a history of liver dysfunction should use this medication with caution, especially when used in conjunction with fibrates or niacin, as there is a risk of serious muscle disorders such as rhabdomyolysis. During treatment with this medication, symptoms such as muscle pain, weakness, abdominal pain, rash, and itching may occur, and liver function and muscle enzyme levels may increase, making regular monitoring necessary. Rhabdomyolysis, a serious muscle disorder, may rarely occur; therefore, if symptoms such as muscle pain or weakness are present, it is important to consult a physician immediately. This medication is not to be administered to pregnant women, women of childbearing potential, or nursing mothers, and safety and efficacy in pediatric patients have not been established. Caution should also be exercised regarding drug interactions, particularly with cyclosporine, fibrates, niacin, and erythromycin, as these can increase the risk of renal impairment and muscle disorders. During treatment with this medication, dietary modification and exercise therapy should be combined, and regular testing of blood lipids and liver functions should be conducted to monitor therapeutic effects and side effects. Elderly patients should be especially careful, as age-related physiological changes may increase the likelihood of adverse reactions. Finally, this medication should be stored out of reach of children and kept in its original container to maintain its quality.

Serious side effects

Urticaria, severe swelling (edema), rhabdomyolysis, acute renal failure, liver dysfunction, jaundice, thrombocytopenia, hypersensitivity, hepatic abnormalities, severe allergic reactions, significant edema or urinary abnormalities, severe neurological symptoms, severe dermatological reactions, respiratory problems, renal impairment, chest tightness, increased blood pressure.

Mild side effects

Abdominal pain, rash, malaise, numbness, itching, headache, dizziness, skin tingling, stiffness, drowsiness, insomnia, heaviness in the head, dry mouth, dyspepsia, abdominal bloating, constipation, stomatitis, vomiting, loss of appetite, glossitis, nausea, gastrointestinal discomfort, diarrhea, granulocytopenia, leukopenia, eosinophilia, leukocytosis, increase in globulin, anemia, polyuria, decreased aldosterone, increased aldosterone, increased adrenal cortex-stimulating hormone, increase in cortisol.

This medication is sensitive to light, so it should be stored in a container that prevents light from entering. In addition, it is recommended to store the medication at room temperature, typically between 1°C and 30°C, to maintain its efficacy for as long as possible.

Appearance

Round film-coated tablet of very light yellow-red color with a score line added.

Package unit

30 tablets/bottle, 100 tablets/bottle