Medication info
Candesartan Cilexetil 80/12.5 mg

Candesartan Cilexetil 80/12.5 mg

Prescription medicationTablet경구
Ingredient · strength
Valsartan›80mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
한국유나이티드제약(주)
Appearance
Bright orange oval film-coated tablet
Packaging
For domestic use: 30 tablets/bottle For export use: 98 tablets (14 tablets/PTP x 7)
Approval status
Active

MFDS item code 201103214 · Notified 2011.05.17 · Insurance code 644308200

Summary

Main use
Improvement in blood pressure control for essential hypertension
Who takes it
Adults
Adult dose
Take 1 tablet of Valsartan 80 mg/Hydrochlorothiazide 12.5 mg once daily with a small amount of water, regardless of meals. Valsartan 160 mg/Hydrochlorothiazide 12.5 mg is applicable when prescribed for blood pressure lowering. For patients with kidney impairment who have mild to moderate kidney impairment, no dosage adjustment is necessary. For patients with liver impairment who do not have cholestasis, it is advisable not to exceed 80 mg per day.

Ingredients

Manufacturer
한국유나이티드제약(주)

Efficacy & effects

Improvement in blood pressure control for essential hypertension

  • Essential hypertension
View approved original text

This medication is used for patients with essential hypertension whose blood pressure is not adequately controlled by monotherapy. In other words, it helps stabilize blood pressure when it is difficult to control with existing medications.

How to take

Adult dose

Take 1 tablet of Valsartan 80 mg/Hydrochlorothiazide 12.5 mg once daily with a small amount of water, regardless of meals. Valsartan 160 mg/Hydrochlorothiazide 12.5 mg is applicable when prescribed for blood pressure lowering. For patients with kidney impairment who have mild to moderate kidney impairment, no dosage adjustment is necessary. For patients with liver impairment who do not have cholestasis, it is advisable not to exceed 80 mg per day.

Precautions

This medication may cause serious harm to the fetus if taken during pregnancy, particularly in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. This medication should not be used in patients with allergies to certain components, in pregnant women, or in patients with severe liver or kidney impairment. Patients with electrolyte imbalances or problems with kidney or liver function should use this medication with caution, and elderly patients or those with cardiovascular diseases should also take the necessary precautions. Dizziness and drowsiness may occur when taking this medication, so caution is advised when driving or operating machinery. It is advisable not to use potassium supplements or potassium-containing medications without consulting a doctor. This medication may increase skin sensitivity to sunlight, so precautions against ultraviolet rays during treatment are necessary, and any abnormal skin symptoms should be discussed with a doctor immediately. Blood pressure may drop suddenly, so extra caution is necessary during excessive sweating, diarrhea, or vomiting. Patients with impaired kidney function should regularly check their potassium and electrolyte levels through blood tests. It is important to periodically monitor liver function and blood test results while taking this medication. In case of overdose, symptoms such as hypotension or arrhythmia may occur, and immediate medical attention is required. This medication is not recommended for children, as its safety and effectiveness have not been established for this population. When taking other medications concurrently, interactions may occur, so it is essential to consult a doctor or pharmacist.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, difficulty breathing or wheezing, asthma attack, cough with fever and respiratory distress, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

  • Headache
  • dizziness
  • nasopharyngitis
  • fatigue
  • back pain
  • cough
  • upper respiratory infections
  • diarrhea
  • joint pain
  • abdominal pain
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  • epigastric pain
  • blurred vision
  • visual disturbances
  • anxiety
  • arthritis
  • bronchitis
  • acute bronchitis
  • chest pain
  • orthostatic dizziness
  • dry mouth
  • dyspepsia
  • erectile dysfunction
  • gastroenteritis
  • excessive sweating
  • sensory impairment
  • insomnia
  • hypokalemia
  • hypotension
  • influenza
  • muscle cramps
  • muscle strain
  • nausea
  • nasal congestion
  • nasal bleeding
  • throat pain
  • otitis media

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to air and moisture, so it should be stored in a tightly sealed container. Additionally, it should be kept in a cool place below 30 degrees Celsius to maintain its effectiveness.

Appearance and packaging

Appearance

Bright orange oval film-coated tablet

Package unit

For domestic use: 30 tablets/bottle For export use: 98 tablets (14 tablets/PTP x 7)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.