Medication info
S-Duo Actin Tablet

S-Duo Actin Tablet

Prescription medicationTablet경구
Ingredient · strength
Atorvastatin Calcium›10.35mg / 1 tabletS-Amlodipine Besylate 2.5 Hydrate›3.74mg / 1 tablet
Manufacturer / importer
안국약품(주)
Appearance
White oval film-coated tablet
Packaging
30 tablets per bottle
Approval status
Active

MFDS item code 201102757 · Approved 2011.04.29

Summary

Main use
(Hypertension, Angina) Reduction of cardiovascular risk and improvement of dyslipidemia
Who takes it
Adults
Adult dose
This medication is prescribed for adults only, and the dosage should be individualized based on the efficacy and tolerance of each component (Amlodipine / Atorvastatin) for each patient. Amlodipine (S-Amlodipine): The adult dose is 5 (2.5) mg orally once a day, and the dose may be increased up to a maximum of 10 (5) mg per day depending on the patient's response. Atorvastatin: 1. For patients with primary hypercholesterolemia and mixed dyslipidemia:

Ingredients

Manufacturer
안국약품(주)

Efficacy & effects

(Hypertension, Angina) Reduction of cardiovascular risk and improvement of dyslipidemia

  • Hypertension
  • fixed obstructive coronary artery disease
  • coronary vasospasm
  • vasoconstriction
  • myocardial ischemia
  • angina
  • risk of vascular interventions
  • risk of cardiovascular diseases
  • multiple risk factors for coronary artery disease
  • myocardial infarction
  • stroke
  • vascular intervention
View approved original text

This medication is used when two components, Amlodipine (S-Amlodipine) and Atorvastatin, are needed together. Amlodipine treats hypertension and angina, especially stable angina and variant angina, and helps reduce the risk of hospitalization due to angina in patients with coronary artery disease and also decreases risks after vascular interventions. Atorvastatin is effective in lowering the risk of cardiovascular diseases such as myocardial infarction and stroke, and in improving serum cholesterol and triglyceride levels. This medication is used to improve conditions in patients with hypertension, coronary artery disease, and dyslipidemia.

How to take

Adult dose

This medication is prescribed for adults only, and the dosage should be individualized based on the efficacy and tolerance of each component (Amlodipine / Atorvastatin) for each patient. Amlodipine (S-Amlodipine): The adult dose is 5 (2.5) mg orally once a day, and the dose may be increased up to a maximum of 10 (5) mg per day depending on the patient's response. Atorvastatin: 1. For patients with primary hypercholesterolemia and mixed dyslipidemia:

Precautions

This medication should not be administered to certain patients. For example, those who are allergic to this medication or similar class of drugs, patients with severely impaired liver function, pregnant or breastfeeding women, patients with severe muscle disorders, patients with severe aortic stenosis, patients in cardiogenic shock, patients within one month after myocardial infarction, patients with unstable angina, and those taking specific hepatitis treatments. Moreover, patients with very poor kidney function, elderly patients, alcoholics or those with a history of liver diseases, patients prone to muscle disorders, patients with acute heart failure, patients in hypertensive crisis, patients with mild to moderate liver dysfunction, and patients with severe myasthenia gravis should use this medication cautiously. While this medication is generally well tolerated, it may rarely cause side effects such as low blood pressure, dizziness, headaches, fatigue, edema, muscle pain, dyspepsia, and liver dysfunction. If liver dysfunction or muscle pain worsens, consult a doctor immediately. Women who may become pregnant should use appropriate contraception while taking this medication and should stop taking it immediately if pregnancy is confirmed. Breastfeeding women are also advised not to take this medication. This medication may interact with other drugs, so if you are taking any other medications, inform your doctor or pharmacist. Extra caution is required when taken with medications that affect liver function or increase the risk of muscle-related side effects. In case of overdose, severe hypotension or heart problems may occur, so the prescribed dosage must be strictly adhered to, and if abnormal symptoms arise, seek medical attention immediately. Finally, the safety and efficacy of this medication has not been sufficiently established in children and the elderly, so caution is advised when used in these age groups under a doctor's guidance.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, paleness, severe rash with fever, blisters, skin peeling, pain in mouth/eye mucosa, shortness of breath or breathing difficulties, asthma attacks, cough with fever-related respiratory issues, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headaches, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

  • Flushing
  • fatigue
  • edema
  • palpitations
  • dizziness
  • headaches
  • drowsiness
  • abdominal pain
  • nausea
  • weakness
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  • malaise
  • pain
  • weight gain/loss
  • hypotension
  • vasculitis
  • muscle tension increase
  • sensory loss/paresthesia
  • peripheral neuropathy
  • syncope
  • altered taste
  • tremor
  • extrapyramidal disturbances
  • erectile dysfunction
  • gynecomastia
  • changes in bowel habits
  • dry mouth
  • dyspepsia
  • gingival hypertrophy
  • gum overgrowth
  • pancreatitis
  • vomiting
  • hyperglycemia
  • arthralgia
  • low back pain
  • muscle cramps
  • muscle

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a tightly closed container. It is advisable to keep the storage temperature between 15 to 30 degrees Celsius. This helps maintain the medication’s effectiveness and safety over time.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets per bottle

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.