Celecoxib Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) : Take 200 mg of celecoxib once daily, or 100 mg per dose twice daily. 2. Rheumatoid arthritis : Take 100 mg or 200 mg of celecoxib per dose twice daily. 3. Ankylosing spondylitis (AS) : Administer 200 mg of celecoxib once daily, or 100 mg per dose twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks at 400 mg daily, another treatment should be considered. 4. Acute pain and primary dysmenorrhea : The initial recommended dose is 400 mg of celecoxib; if needed, an additional 200 mg may be administered on the first day of treatment. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment : In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be consulted with a doctor or pharmacist if the patient consumes alcohol in amounts greater than a certain limit daily, as it may lead to gastrointestinal bleeding. This medication may increase the risk of cardiovascular problems such as heart attack or stroke. This risk may be greater depending on the dosage and duration of use, so it should be used at the lowest effective dose for the shortest duration possible. There is a risk of developing gastrointestinal ulcers or bleeding, especially in the elderly or those with a history of gastrointestinal disorders. If symptoms such as epigastric pain, indigestion, black stools, or hematemesis occur, medical attention should be sought immediately. Patients with a known allergy to this medication, severe asthma, heart, liver or kidney diseases, pregnant or breastfeeding women, and those with certain genetic disorders should not take this drug. Those with liver or kidney impairment, hypertension, heart failure, or diabetes should use this medication with caution, and should regularly monitor their health status according to their doctor's advice. This medication can interact with various drugs, so if the patient is taking other medications, they should inform their healthcare professional. Caution is especially needed when taken alongside blood pressure medications, diuretics, anticoagulants, and antidepressants. Women who are pregnant or planning to become pregnant should consult a healthcare professional before taking this medication, as it may affect fertility. This medication may cause dizziness or drowsiness, so it is advisable to avoid driving or operating machinery. Patients who take this medication for a long time should have regular blood tests and checks on liver and kidney function to detect any abnormalities early and take appropriate action. If skin rashes, itching, or blisters occur, discontinue use immediately and consult a healthcare professional. Overdose may cause symptoms such as vomiting, lethargy, drowsiness, and requires immediate emergency treatment. This medication is not recommended for use in children and adolescents as its safety and efficacy have not been established.

Gastrointestinal hemorrhage, cardiovascular thrombotic events, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, indigestion, abdominal distension, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechial hemorrhage, angioedema, alopecia, bullous dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, headache, leg cramps, tension hypertonicity, sensory decline, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, olfactory loss, taste loss, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, septicemia, sudden death, anaphylactic-like reaction, angioedema, loss of appetite, increased appetite, depression, neuroexcitability, drowsiness, fatal intracranial hemorrhage, hallucinations, worsening of epilepsy, upper respiratory tract infection, sinusitis, pharyngitis, rhinitis, bronchitis, bronchospasm, exacerbation of bronchospasm, shortness of breath, laryngitis, pneumonia, nosebleed, voice disorders, vesicular dermatitis, dermatitis, nail disorders, photosensitivity reactions, pruritus, erythematous rash, maculopapular rash, skin diseases, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, skin-mucous membrane syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash with eosinophilia and systemic symptoms, arrhythmia, left ventricular hypertrophy, angina, unstable angina, coronary artery disease, heart failure, palpitations, tachycardia, aortic valve insufficiency, hematoma, bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, thrombotic venous disease, vasculitis, deep vein thrombosis, cerebral hemorrhage, shingles, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, breast neoplasm, chest pain, dysmenorrhea, menstrual disorders, vaginal hemorrhage, vaginitis, prostate disorder, ovarian cyst, hearing loss, ear abnormalities, otalgia, hearing impairment, liver function abnormalities, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, increased blood sodium, increased blood potassium, elevated BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, elevated LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, osteopathy, myalgia, cervical dystonia, synovitis, tendinitis, myositis, fracture, tendon rupture, back pain, muscle stiffness, decreased hematocrit, increased hemoglobin, nosebleed, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, granulomatous inflammation, contact dermatitis, injection site reactions, skin nodules, dysgeusia, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, kidney dysfunction, acute renal failure, interstitial nephritis, menstrual disorders, chest pain, anaphylactic reaction, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized pustular rash, exfoliative dermatitis, general bullous fixed drug eruption, fixed drug eruption, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, microangiopathy glomerulonephritis, female infertility

This medication should be stored in a tightly sealed container to prevent air ingress, and the recommended storage temperature is between 15 to 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness for a longer period.

Appearance

An opaque hard capsule filled with white to light yellow powder with yellow stripes on the top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle