Selbit Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) : Take 200 mg of celecoxib once daily, or 100 mg per dose twice daily. 2. Rheumatoid arthritis : Take 100 mg or 200 mg of celecoxib per dose twice daily. 3. Ankylosing spondylitis (AS) : Administer 200 mg of celecoxib once daily, or 100 mg per dose twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks at 400 mg daily, another treatment should be considered. 4. Acute pain and primary dysmenorrhea : The initial recommended dose is 400 mg of celecoxib; if needed, an additional 200 mg may be administered on the first day of treatment. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment : In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be used with caution in individuals who regularly drink alcohol in amounts exceeding a certain level daily, as it may pose a risk of gastrointestinal bleeding, requiring consultation with a doctor or pharmacist. This medication may increase the risk of serious cardiovascular side effects such as thrombotic events, myocardial infarction, and stroke. This risk may escalate based on the dosage and duration of treatment, hence it should be used at the lowest effective dose for the shortest duration possible. If symptoms of cardiovascular abnormalities such as chest pain, shortness of breath, weakness, or speech difficulties occur while taking this medication, immediate consultation with a healthcare provider is necessary. This medication may cause serious gastrointestinal side effects, including gastrointestinal perforation, ulceration, or bleeding; therefore, special caution should be exercised in the elderly or those with a history of gastrointestinal disease. If symptoms of gastrointestinal bleeding or ulceration occur, such as epigastric pain, dyspepsia, black stools, or hematemesis, immediate medical attention is required. This medication should not be administered to specific patients such as those with certain allergies, severe liver or kidney diseases, active peptic ulcer disease, heart failure, pregnant or nursing women. Patients with reduced liver or kidney function, asthma, hypertension, or edema should use this medication more cautiously, requiring regular monitoring and assessments. Various side effects have been reported with this medication, including dyspepsia, headache, dizziness, hypertension, rash, hepatic dysfunction, and renal impairment. Especially, if symptoms such as skin rash, itching, blistering, or fever occur, the medication should be immediately discontinued and healthcare advice sought. This medication may interact with other drugs, so if you are taking any other medications, be sure to inform your healthcare provider or pharmacist, and regular tests like liver or kidney function and blood pressure checks are necessary. Women who are pregnant or planning to become pregnant should avoid taking this medication, and nursing mothers should also refrain from using it. Activities requiring caution, such as driving or operating machinery, should be avoided while taking this medication. In the case of overdose, symptoms such as nausea, vomiting, drowsiness, or lethargy may appear, and immediate medical attention should be sought.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, hives, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial swelling, influenza-like illness, injuries, taste distortion, albuminuria, cystitis, hematuria, dysuria, frequent urination, nephrolithiasis, urinary incontinence, visual disturbances, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, headache, leg cramps, sensory disturbance, migraine, neuralgia, neuropathy, sensory anomalies, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, allergy exacerbation, allergic reactions, weakness, chest pain, fluid retention, generalized edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, angioedema, loss of appetite, increased appetite, depression, nervous hyperreactivity, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory infection, shingles, wound infections, gingivitis, herpes simplex, herpes zoster, bacterial infections, fungal infections, soft tissue infections, viral infections, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic changes of the breast, thoracic tumors, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver function abnormalities, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, elevated serum sodium, elevated serum potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, increased LDH, hypoglycemia, hyponatremia, synovial sac, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical tension, synovitis, tendonitis, myositis, fractures, tendon rupture, pain in various locations, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, vaginitis, contact dermatitis, injection site reactions, skin nodules, visual disturbances, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, acute renal failure, hyponatremia, cholestasis, cholestatic hepatitis, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug-induced rash, acute generalized pustular rash, exfoliative dermatitis, generalized fixed drug eruption, fixed drug eruption, tubular interstitial nephritis, nephrotic syndrome, minifocal glomerulonephritis, female infertility, chest pain, thirst, ulcerative stomatitis, gastritis, allergy, back pain, hyperlipidemia, diabetes, weight gain, pneumonia, dyspnea, hearing loss, epistaxis, voice disorders, pulmonary embolism, interstitial pneumonia

This medication should be stored in a tightly sealed container to prevent air entry, at a recommended temperature between 15 degrees Celsius and 30 degrees Celsius. This preserves the drug's effectiveness and prevents degradation.

Appearance

Capsules with a white to off-white powder filling

Package unit

30 capsules/bottle, 100 capsules/bottle