Celebrex Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered with or without food. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg per dose twice daily. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib per dose twice daily. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg per dose twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks at 400 mg daily, another treatment should be considered. Acute pain and primary dysmenorrhea: The initial recommended dose is 400 mg of celecoxib; if needed, an additional 200 mg may be administered on the first day of treatment. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may increase the risk of gastrointestinal bleeding in individuals who regularly consume three or more alcoholic beverages daily, so it is essential to consult a doctor or pharmacist. This medication may increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke, and it should only be used for the lowest effective dose and the shortest duration. If cardiovascular symptoms occur, notify medical personnel immediately. Serious gastrointestinal issues such as ulcers, bleeding, and perforation may occur, especially in elderly patients or those with a history of gastrointestinal disorders, so caution is advised. This medication should not be administered to patients with certain allergies, those with severely impaired liver or kidney function, pregnant women or those who may become pregnant, and breastfeeding mothers. Caution is necessary for patients with pre-existing conditions such as impaired liver or kidney function, hypertension, heart failure, or asthma, and regular monitoring is required. Dizziness or drowsiness may occur, so it is advisable to avoid driving or operating machinery. This medication may interact with several other medications, so individuals taking other medications should inform their healthcare provider, especially when taking blood pressure medications, anticoagulants, or antidepressants. Use during pregnancy may pose risks to the fetus, so pregnant or planning to become pregnant women should avoid using this medication, and breastfeeding mothers should consult a professional. Long-term use of this medication may affect kidney or liver function, so regular blood tests and health checks are necessary. Overdose may result in symptoms such as vomiting, lethargy, and renal failure, so it is crucial to adhere to the prescribed dosage and contact healthcare personnel immediately if any unusual symptoms occur. Store this medication out of the reach of children and do not transfer it to another container.

Gastrointestinal bleeding, cardiovascular thrombotic events, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, frequency of urination, nephrolithiasis, urinary incontinence, urinary tract infection, visual disturbance, cataract, conjunctivitis, eye pain, glaucoma, retinal artery or vein occlusion, elevated serum creatinine, increased β2-microglobulin, elevated NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, elevated serum sodium, elevated serum potassium, increased BUN, elevated CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, decreased appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical strain, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in the neck and back, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, nosebleed, thrombasthenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, pyoderma, contact dermatitis, injection site reactions, subcutaneous nodules, headache, migraine, neuralgia, neuropathy, sensory disturbances, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reactions, angioedema, decreased appetite, increased appetite, depression, nervous irritability, sleepiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory infection, bronchospasm, exacerbation of bronchospasm, shortness of breath, laryngitis, pneumonia, nosebleed, speech disorders, vesicular dermatitis, dermatitis, nail diseases, photosensitivity reactions, pruritus, erythematous rash, maculopapular rash, skin diseases, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, mucous membrane syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechial hemorrhage, dandruff, drug rash accompanied by eosinophilia and systemic symptoms, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, acute renal failure, tubular interstitial nephritis, nephrotic syndrome, minor lesion glomerulonephritis, menstrual disorders, female infertility, chest pain, anaphylactic reaction, hallucinations, cerebral hemorrhage

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. Moreover, it is best stored at room temperature between 15 to 30 degrees Celsius, not in excessively hot or cold places.

Appearance

A white capsule filled with white to slightly yellow powder with yellow stripes on the top and bottom

Package unit

30 capsules per bottle, 100 capsules per bottle