Roxfen CR Tablet (Loxoprofen Sodium)

Adult dose

Adults: Take 90 mg of loxoprofen sodium (anhydrous) orally twice a day. This medication should be swallowed whole without crushing, chewing, or dissolving.

This medication may cause gastrointestinal bleeding in individuals who regularly consume more than three drinks a day, so consultation with a doctor or pharmacist is essential. This medication may increase the risk of cardiovascular diseases, so patients with a history of heart disease or stroke, or who have risk factors, should be especially cautious. It can cause serious gastrointestinal issues such as gastrointestinal bleeding, ulcers, or perforations, making elderly patients or those with a history of gastrointestinal diseases particularly careful. Patients with peptic ulcers, severe blood disorders, liver impairment, kidney impairment, heart failure, or a history of hypersensitivity to the drug should not take this medication. Women in late pregnancy or nursing mothers should also not use this drug. Hypersensitivity reactions may include rashes, itching, hives, and in severe cases, life-threatening reactions such as shock or anaphylaxis may occur, so stop taking the drug immediately if symptoms arise. Gastrointestinal symptoms may include abdominal pain, nausea, vomiting, diarrhea, etc., and in severe cases, gastrointestinal bleeding or bowel perforation may occur, so seek medical advice if abnormal symptoms occur. Various adverse reactions such as liver dysfunction, kidney impairment, blood disorders, respiratory distress, skin rash, etc., have been reported, so patients should carefully observe their condition while taking the medication. The risk of adverse effects increases when this drug is taken with other non-steroidal anti-inflammatory drugs (NSAIDs), so it is advisable not to combine them. It may interact with specific blood pressure medications, anticoagulants, antibiotics, lithium, methotrexate, etc., so if taking other medications, consult a doctor. Use cautiously in early and mid-pregnancy, and absolutely avoid during late pregnancy as it may pose risks to the fetus. Nursing mothers should not take this medication, and safety in children has not been established. Elderly patients have a higher risk of adverse effects, so extra caution is necessary during use. This drug should be used at the minimum effective dosage for the shortest period possible, and regular check-ups and monitoring by a physician are required for long-term use. Store away from children’s reach and do not transfer to other containers for safety.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, shock, symptoms resembling anaphylaxis, asthma attacks, peptic ulcers, hematemesis, gastrointestinal bleeding, melena, shock, bowel perforation, severe rashes, blisters, skin peeling, pain in mucous membranes of mouth/eyes, liver dysfunction (jaundice), fulminant hepatitis, liver necrosis, liver failure, acute renal failure, respiratory distress, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell syndrome),

Mild side effects

• Rash
• itching
• fever
• abdominal pain
• discomfort in the stomach
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1°C and 30°C.

Appearance

Pale yellow round enteric-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle