Olmesartan Medoxomil Tablet 20mg

Adult dose

The recommended initial dose is 10mg once daily, administered regardless of meals. If blood pressure is not adequately controlled at this dose, it may be increased to 20mg once daily. If additional blood pressure reduction is needed, the maximum daily dose may be increased to 40mg. The antihypertensive effect appears within 2 weeks of starting treatment, with the maximum effect appearing after approximately 8 weeks. If blood pressure is not controlled with monotherapy, it can be combined with thiazide diuretics such as hydrochlorothiazide.

Child dose

Safety and efficacy in pediatric patients have not been established.

This medication may cause serious harm or death to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. It is prohibited for use in individuals allergic to any ingredients in this medication, pregnant women, nursing mothers, patients undergoing kidney dialysis, patients with severe liver impairment, patients with biliary obstruction, and certain genetically lactose intolerant patients. Patients with reduced blood volume or sodium may experience hypotension, so their condition should be carefully evaluated before administration, and blood pressure changes should be closely monitored during treatment. Patients with kidney dysfunction or those who have received a kidney transplant may experience changes in kidney function while taking this medication, so regular blood tests are necessary. There is a risk of elevated serum potassium levels while taking this medication, so patients with heart failure or kidney disease should regularly check their potassium levels. Patients with heart-related conditions such as aortic stenosis, mitral valve stenosis, or obstructive cardiomyopathy should take caution while using this medication. This medication may cause side effects such as dizziness, so caution is advised during dangerous tasks such as operating machinery or driving. Common side effects that may occur include dizziness, headache, back pain, indigestion, palpitations, rash, etc., most of which are temporary and mild symptoms. Rarely, serious adverse reactions such as angioedema, liver dysfunction, hyperkalemia, and acute renal failure may occur, so immediate consultation with medical personnel is needed if symptoms arise. If chronic diarrhea or weight loss persists, it may be indicative of a chronic malabsorption-like gastrointestinal disorder related to this medication, so use should be discontinued and a physician consulted. Co-administration with other antihypertensive agents, potassium-sparing diuretics, or potassium supplements may lead to dangerously elevated potassium levels, so caution is needed with combination therapy. Concomitant use with lithium may increase lithium concentration, leading to toxicity, so co-administration should be avoided. Co-administration with non-steroidal anti-inflammatory drugs may increase the risk of renal function impairment, so hydration and monitoring of kidney function are necessary. Ideally, this medication should be avoided during pregnancy, particularly in the second and third trimesters, and if unavoidable, the condition of the fetus should be regularly monitored through ultrasound or other means. If breastfeeding, it is recommended to either discontinue breastfeeding or the medication, as it may be passed into breast milk. Safety and efficacy in pediatric patients have not been adequately established, so it is better not to use it in children. Elderly patients may experience slower drug metabolism, so dose adjustment and careful observation are required when administering this medication. In cases of overdose, hypotension and palpitations may occur, and appropriate emergency treatment is necessary if symptoms are severe. This medication does not provide evidence of carcinogenicity or genotoxicity even with long-term use; however, rare experimental results related to cell mutations have been reported, so caution is necessary.

Serious side effects

Hives, severe swelling (including angioedema and facial edema), chest tightness, difficulty breathing, anaphylaxis, severe rash accompanied by fever, blisters, skin peeling, oral/ocular mucosal pain, intestinal vascular swelling, skin adverse reactions including hair loss, yellowing of the skin or eyes (jaundice), liver dysfunction (including autoimmune hepatitis), sudden and severe headache, seizures, confusion, visual disturbances, paralysis, dyspnea

Mild side effects

Dizziness, headache, palpitations, hypercholesterolemia, hyperlipidemia, hyperuricemia, arthralgia, arthritis, myalgia, abdominal pain, indigestion, gastroenteritis, nausea, diarrhea, back pain, hematuria, cough, epistaxis, upper respiratory infection, flu-like symptoms, pharyngitis, rhinitis, sinusitis, alopecia, pruritus, chest pain, peripheral edema, increased serum creatinine, elevated blood pressure (some mild cases)

This medication should be stored in a tightly closed container to avoid contact with air or moisture, and it is advisable to keep it at room temperature between 1 degree and 25 degrees Celsius. Proper storage helps maintain the medication's effectiveness for a long time.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle