Olmesartan Medoxomil Hydrochlorothiazide Plus Tablet

Adult dose

This medication is to be taken once daily with or without food. Dosage should be adjusted every 2 to 4 weeks based on the patient's blood pressure response. In the elderly, treatment should start at the lowest dose, and dosage adjustments must take into account kidney function, heart function, comorbid conditions, and concomitant medications.

Child dose

Safety and efficacy in children have not been established.

This medication may cause serious harm or death to the fetus or newborn if taken during the second and third trimesters of pregnancy, therefore it should be discontinued immediately upon confirmation of pregnancy. It should not be used in patients with allergies to this drug or its components, specific kidney or liver diseases, or in women who are pregnant or breastfeeding. Patients with significantly low blood pressure, severely impaired kidney function, and certain electrolyte abnormalities should use this medication with caution, and their conditions should be closely monitored before and during treatment. As this medication lowers blood pressure, dizziness or symptoms of hypotension may occur when starting treatment, and appropriate actions should be taken if symptoms arise. It can affect kidney function; therefore, patients with impaired kidney function should have regular blood tests to check kidney status. Patients with severely impaired liver function or certain heart diseases also require caution, and electrolyte imbalances or dehydration should be managed. This medication may increase the risk of skin cancer; therefore, sun exposure should be minimized, and any skin abnormalities should be immediately consulted with a doctor. During treatment, symptoms such as dizziness, headache, indigestion, muscle pain, rash, and others may occur, and if there are severe edema or breathing difficulties, healthcare personnel should be informed immediately. This medication can interact with other drugs; therefore, especially if taking potassium supplements, diuretics, lithium, or anti-inflammatory drugs, it is essential to inform healthcare personnel and be cautious. Pregnant and breastfeeding women should pay special attention to taking this medication, and breastfeeding should be avoided or paused while taking this medication. In children and the elderly, the safety and efficacy of this medication have not been well established, or there may be impaired kidney function, so dosage adjustments and caution are necessary. In cases of overdose, symptoms such as hypotension, electrolyte imbalance, and dehydration may occur, and appropriate treatment should be received at a medical institution immediately. Regular blood tests and monitoring of electrolytes, kidney function, and liver function during medication use are important.

Serious side effects

Urticaria, severe swelling (edema), angioedema, anaphylactic reaction, severe skin adverse reactions, urticaria, angioedema, facial swelling, liver abnormalities (jaundice), jaundice, acute renal failure, acute respiratory distress syndrome (ARDS), breathing difficulties, asthma attacks, severe hypotension, kidney function impairment, seizures, confusion, visual disturbances, paralysis, severe neurological symptoms, hyponatremia, frequent urination, severe edema, hyperkalemia, urinary difficulties

Mild side effects

• Nausea
• dizziness
• upper respiratory infection
• headache
• urinary tract infection
• chest pain
• back pain
• peripheral edema
• lightheadedness
• abdominal pain

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is advisable to maintain a storage temperature between 1°C and 25°C. By storing it this way, the effectiveness and safety of the medication can be maintained for a long time.

Appearance

Round film-coated tablet with yellowish color

Package unit

30 tablets/bottle, 100 tablets/bottle