Olmesartan Medoxomil 20 mg

Adult dose

The recommended initial dose is 10 mg once daily, taken regardless of meals. If blood pressure is not adequately controlled at this dose, it may be increased to 20 mg once daily. If necessary, the dose can be increased up to a maximum of 40 mg once daily. The blood pressure-lowering effect occurs within 2 weeks of starting treatment, with the maximum effect seen after approximately 8 weeks. If blood pressure remains uncontrolled, this medication may be combined with thiazide diuretics.

Child dose

Safety and efficacy for pediatric patients have not been established; therefore, it is not recommended.

This medication should not be given to women in the second and third trimesters of pregnancy. It carries the risk of serious damage or even death to the fetus or newborn. If pregnancy is confirmed, this medication must be discontinued immediately. It should not be used if there is an allergy to any ingredients contained in this medication. In addition, women who are pregnant or breastfeeding, patients undergoing kidney dialysis, patients with severe liver impairment, and patients with bile duct obstruction should not use this medication. Individuals with certain genetic disorders, such as lactose intolerance, should also not take this medication. Diabetic patients taking the medication aliskiren or those with moderate to severe kidney dysfunction should not use this drug concurrently. When this medication is first administered to patients with low blood volume or salt deficiency, blood pressure can drop suddenly; caution is required in these cases. The patient should be laid down, and if necessary, saline solution should be administered to stabilize blood pressure. Patients with severe heart failure and poor kidney function may experience worsening of kidney function when taking this medication, necessitating regular blood tests. Kidney transplant patients or patients with renal artery hypertension should also carefully monitor kidney function while taking this medication. Due to the risk of hyperkalemia, patients with heart or kidney conditions should have their serum potassium levels checked regularly. Special caution is required when prescribing this medication to patients with aortic stenosis, mitral valve stenosis, obstructive hypertrophic cardiomyopathy, or echocardiographic evidence of left ventricular outflow tract obstruction. Patients with primary aldosteronism may not respond well to this medication, and its use is not recommended. This medication lowers blood pressure, which may result in dizziness; therefore, caution should be exercised when driving or operating dangerous machinery. Common side effects that may occur during the use of this medication include dizziness, headache, back pain, dyspepsia, and cough, most of which are mild and temporary. Serious allergic reactions, such as facial swelling or angioedema, may occur in rare cases; any unusual symptoms should be reported to a healthcare professional immediately. Long-term use may rarely result in abnormal liver function tests or changes in blood test values, so regular testing is necessary. This medication may increase the blood pressure-lowering effect when taken with other antihypertensive drugs, so consultation with a healthcare provider is advised. Taking potassium-sparing diuretics or potassium supplements concurrently may raise potassium levels to dangerous levels, requiring caution. When combined with non-steroidal anti-inflammatory drugs, kidney function may worsen; therefore, adequate hydration and monitoring of kidney function are necessary. This medication may increase lithium levels when taken with lithium, leading to toxicity; therefore, concurrent use is not recommended. Taking this medication during pregnancy can lead to serious side effects for the fetus; therefore, it is essential to consult with a healthcare provider if pregnancy is planned or if the patient is pregnant. Women who are breastfeeding should be aware that this medication can be partially transmitted in breast milk, posing a risk of adverse reactions to the baby; thus, it is advisable to cease breastfeeding or discontinue the medication. Safety and efficacy in pediatric patients have not yet been established. Elderly patients may require dose adjustments due to altered drug metabolism; therefore, they should follow healthcare provider instructions regarding dosage. In case of overdose, symptoms such as hypotension or palpitations may appear, and in severe cases, bradycardia may occur, necessitating appropriate treatment based on the symptoms. No significant carcinogenic or genotoxic risks have been reported in carcinogenicity or genetic toxicity tests; however, any unusual reactions during clinical use should be reported to healthcare professionals immediately.

Serious side effects

Hives, severe swelling (edema), angioedema, anaphylaxis, hyperkalemia, acute renal failure, increased serum creatinine, abnormal liver function tests (increased transaminases or total bilirubin), severe allergic reactions, severe edema or urination abnormalities

Mild side effects

• Dizziness
• headache
• palpitations
• back pain
• bronchitis
• creatine phosphokinase increase
• diarrhea
• hematuria
• hyperglycemia
• hypertriglyceridemia

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is recommended to maintain storage temperatures between 1 degree and 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle