Belmetec Tablets 10 mg (Olmesartan Medoxomil)

Adult dose

The recommended initial dose is 10 mg once daily, administered regardless of food intake. If blood pressure remains inadequately controlled at this dose, it may be increased to 20 mg once daily. If further blood pressure reduction is required, the dose may be increased to a maximum of 40 mg once daily. The antihypertensive effect appears within 2 weeks after starting treatment, with maximum effect observed after approximately 8 weeks. If blood pressure remains uncontrolled with monotherapy, thiazide diuretics such as hydrochlorothiazide may be added. To improve compliance, it is recommended to take the medication at the same time each day (e.g., in the morning). For patients at risk of intravascular volume depletion (e.g., those on diuretics, particularly those with kidney impairment), it is recommended to start treatment at a lower dose while monitoring their condition closely. <For Elderly Patients> There is no need for dose adjustment when administering this medication to patients aged 65 years or older. No significant differences have been observed in efficacy and safety between elderly and younger patients; however, it cannot be excluded that some elderly patients may exhibit a more sensitive response. <For Patients with Kidney Impairment> For patients with mild to moderate kidney impairment (creatinine clearance of 20-60 mL/min), the maximum dosage is 20 mg once daily. <For Patients with Liver Impairment> Patients with mild liver impairment do not require dose adjustment. The recommended initial dose for patients with moderate liver impairment is 10 mg once daily, with a maximum increase to 20 mg daily. There is insufficient experience with severe liver impairment; therefore, use of this medication is not recommended. <For Children> Safety and efficacy have not been established in pediatric patients.

This medication can cause severe harm to the fetus and newborn if taken during the 2nd and 3rd trimesters of pregnancy; therefore, it must be discontinued immediately upon confirmation of pregnancy. Individuals allergic to any ingredients in this medication, pregnant or breastfeeding women, patients undergoing renal dialysis, patients with severe liver impairment, and those with biliary obstruction should not take this medication. Patients with a genetic disorder that prevents lactose digestion should also refrain from taking this medication. Patients with low blood volume or inadequate sodium levels may experience hypotension when beginning this medication, necessitating caution, and appropriate measures should be taken immediately if hypotension occurs during treatment. Patients with severe heart failure or very poor kidney function may see worsening kidney function from taking this medication, so regular blood tests are necessary. Due to its blood pressure-lowering effects, dizziness may occur, so driving or operating dangerous machinery is not advised. This medication may pose a risk of hyperkalemia; potassium levels should be monitored regularly, and extra caution is required if taking potassium supplements or potassium-sparing diuretics. When taken alongside other antihypertensives, blood pressure may drop too low; therefore, it should be taken according to a physician's instructions. Co-administration of lithium preparations with this medication can dangerously elevate lithium levels; hence, their combined use should be avoided. Taking this medication alongside non-steroidal anti-inflammatory drugs may risk kidney function deterioration, so adequate hydration and regular monitoring of renal function are necessary. This medication may rarely cause gastrointestinal issues such as chronic diarrhea with long-term use; if any abnormal symptoms appear, consult a physician. If symptoms such as skin rashes, itching, or swelling of the face or neck occur during treatment, inform healthcare personnel immediately. Pregnant women taking this medication risk severe complications for the fetus, so those planning to become pregnant or currently pregnant should definitely consult healthcare personnel. Breastfeeding women are advised to either stop breastfeeding or discontinue this medication as it may pass into breast milk. Safety and efficacy in pediatric patients have not been sufficiently established, so it is recommended that children do not take this medication. Elderly patients may have higher concentrations of this medication in their system, so caution is necessary when administering it. Overdose may cause hypotension or heart rhythm disturbances, and immediate medical assistance is required. This medication is known to have a low risk of carcinogenicity even with long-term use; however, any abnormal symptoms during treatment should be discussed with a healthcare provider.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe allergic reaction with high fever and rash, blisters, skin peeling, mucosal pain in the mouth/eyes, severe skin reactions, asthma attacks, respiratory issues accompanied by cough and fever, jaundice, extreme lethargy, liver abnormalities (jaundice), acute renal failure, increased blood creatinine levels

Mild side effects

• Dizziness
• headache
• palpitations
• back pain
• cough
• hematuria
• dyspepsia
• nausea
• abdominal pain
• diarrhea

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain storage temperatures between 1 and 25 degrees Celsius. Proper storage helps maintain the medication's efficacy and safety.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle