Olmesartan Medoxomil 20 mg Tablets

Adult dose

In adults, the recommended initial dose is 10 mg once daily, regardless of meals. If blood pressure is not adequately controlled at this dose, it can be increased to 20 mg once daily, with a maximum dose of 40 mg once daily. Antihypertensive effects typically appear within 2 weeks after starting treatment, with maximum effect observed after about 8 weeks. If blood pressure is not adequately controlled with this medication alone, it can be used in combination with thiazide diuretics.

Child dose

Safety and efficacy in children have not been established, and clear dosing guidelines are not available.

This drug can cause serious harm or death to the fetus and newborn if taken during the second and third trimesters of pregnancy, so treatment must be discontinued immediately upon confirmation of pregnancy. It should not be used in patients allergic to any of its ingredients, patients undergoing renal dialysis, patients with severe liver impairment, patients with biliary obstruction, and certain genetically predisposed patients with lactose intolerance. Special caution should be exercised in patients with low blood volume or low sodium, as hypotension may occur, and patients with impaired renal function or kidney transplant recipients should have their renal function and potassium levels monitored regularly through blood tests. This medication carries a risk of hyperkalemia, so patients with heart failure or impaired renal function should carefully monitor potassium levels in the blood. Patients with aortic or mitral valve stenosis and obstructive cardiomyopathy need special caution when taking this medication. Dizziness may occur during treatment, so it is advisable to avoid high-altitude tasks or operating hazardous machinery while on this medication. Common side effects may include dizziness, headache, abdominal pain, nausea, palpitations, and rash, while rare side effects can include angioedema or liver dysfunction. If chronic diarrhea and weight loss occur, discontinue use and consult a physician. This medication may interact with potassium-sparing diuretics, potassium supplements, lithium, and non-steroidal anti-inflammatory drugs, so it is crucial to inform healthcare providers of any other medications being taken. Pregnant or breastfeeding women should avoid this medication, especially during pregnancy, as it could pose risks to the fetus, requiring immediate cessation of use. Safety in children has not been established, and caution is advised in the elderly as drug concentration in the body may increase. In case of overdose, symptoms like hypotension or palpitations may occur, requiring immediate medical attention. While this medication is known to have a low risk of carcinogenic or genotoxic effects with prolonged use, it is important to consult a physician before and after treatment.

Serious side effects

Urticaria, angioedema, facial swelling, anaphylaxis, intestinal vascular edema, rhabdomyolysis, hyperkalemia, acute renal failure, increased serum creatinine, liver dysfunction (elevated liver enzymes or bilirubin, autoimmune hepatitis), urticaria

Mild side effects

• Dizziness
• headache
• palpitations
• low back pain
• bronchitis
• increased creatine phosphokinase
• diarrhea
• hematuria
• hyperglycemia
• hypertriglyceridemia

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. The recommended storage temperature is between 1 and 25 degrees Celsius at room temperature. Proper storage helps maintain the potency of the medication for an extended period.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle