Crecox Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this drug should be adjusted for each patient, and it may be administered regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg daily may be administered. If no effect is observed after 6 weeks of treatment with 400 mg daily, another treatment should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment : In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This drug should be consulted with a doctor or pharmacist if taken by individuals who regularly consume more than three alcoholic beverages daily, as this may lead to gastrointestinal bleeding. This drug may increase the risk of cardiovascular thrombotic events such as heart attack or stroke, so it should be used at the lowest possible dose and for the shortest duration. There is a risk of developing ulcers or bleeding in the gastrointestinal tract, and caution should be taken, especially for elderly patients or those with a history of gastrointestinal disease. This drug should not be used by patients with certain allergies or severe liver, kidney, or heart diseases, as well as by women who are pregnant or breastfeeding. Patients with impaired liver or kidney function, or a history of hypertension, asthma, or heart failure should use this drug with caution and follow their doctor's instructions. Blood pressure, liver function, and kidney function should be regularly monitored during treatment, and if any abnormal symptoms occur, medical personnel should be notified immediately. This drug may interact with other medications, so if the patient is taking any other medications, they should inform their doctor or pharmacist, especially if taking antihypertensives, anticoagulants, or antidepressants. Women who are pregnant or planning to become pregnant should consult before use as this drug may affect reproductive ability, and usage should be avoided during pregnancy. Dizziness or drowsiness may occur after taking this drug, so it is advisable to avoid hazardous tasks such as driving or operating machinery. Long-term users of this drug should have regular blood tests and tests for liver and kidney function, and if severe skin reactions or allergic symptoms occur, use should be discontinued immediately. In the event of overdose, symptoms such as nausea, vomiting, and lethargy may occur, and immediate medical attention is required.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial edema, influenza-like illnesses, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, urinary frequency, kidney stones, urinary incontinence, urinary tract infections, visual confusion, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased blood creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, headache, leg cramps, sensory decline, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reactions, angioedema, loss of appetite, increased appetite, depression, nervous irritability, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory tract infections, herpes simplex, wound infections, gingivitis, herpes zoster, bacterial infections, fungal infections, soft tissue infections, viral infections, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic changes of the breast, thoracic neoplasms, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, sensorineural hearing loss, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urinary urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased sodium in the blood, increased potassium in the blood, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, fractures, tendon ruptures, pain in various parts, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic fasciitis, contact dermatitis, injection site reactions, cutaneous nodules, visual confusion, conjunctivitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rashes accompanied by eosinophilia and systemic symptoms, acute generalized pustular rash, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change glomerulonephritis, female infertility

This drug should be stored in a tightly closed container to prevent air intrusion and kept in a cool place between 15 and 30 degrees Celsius. Proper storage helps maintain the efficacy of the medication.

Appearance

A hard capsule filled with white to light yellow powder with yellow stripes on the cap and body.

Package unit

Domestic use - 100 capsules/bottle, Domestic use - 30 capsules/bottle, Export - 30 capsules/box [10 tablets/PTP*3], Export - 100 capsules/box [10 tablets/PTP*10]