Donghwa Amlodipine Besilate Tablets 10 mg

Adult dose

Administer 5 mg orally once daily as amlodipine, and may be increased to a maximum of 10 mg daily according to patient response. Adjust according to age and symptoms as appropriate.

This medication should not be used in certain patients. It is contraindicated in individuals with allergies to this medication or similar drugs, nursing mothers, patients with severe liver dysfunction, those with severe aortic stenosis, and patients in shock. Furthermore, caution is advised in patients with severe hypotension, those requiring dialysis due to kidney failure, the elderly, and women who are pregnant or may become pregnant. Common side effects may include flushing, fatigue, swelling, palpitations, dizziness, headaches, drowsiness, abdominal pain, and nausea. Rarely, serious adverse reactions such as hypotension, vasculitis, neurological symptoms, gastrointestinal issues, liver dysfunction, and skin rashes may be reported. Patients with heart failure or liver dysfunction should be more cautious in using this medication, and the antihypertensive effects may slowly diminish after discontinuation, requiring care when concomitantly using other antihypertensives. Taking this medication with grapefruit juice may enhance the blood pressure-lowering effects, so it is advisable to avoid this combination. Additionally, interactions may occur with certain medications, and patients should inform their doctor or pharmacist if they are taking other drugs. Women who are pregnant are advised not to use this medication unless in special circumstances, and it is recommended for nursing mothers to discontinue breastfeeding while on this medication. The medication is only suitable for children aged 6 years and older; its efficacy and safety have not been established in children under 6 years old. In case of overdose, severe hypotension, tachycardia, and shock may occur, necessitating immediate medical attention. This medication is not removed by hemodialysis, so caution is necessary. It is known not to significantly affect driving or machinery operation abilities, but caution is advised in the event of any side effects.

Serious side effects

• Urticaria
• angioedema
• toxic epidermal necrolysis
• rash
• jaundice
• hepatitis
• difficulty breathing
• shortness of breath
• pulmonary edema.

Mild side effects

• Flushing
• fatigue
• swelling
• palpitations
• dizziness
• headaches
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, ideally at room temperature between 1°C and 30°C. Proper storage will help maintain the medication's efficacy.

Appearance

White octagonal tablet

Package unit

30 tablets/bottle