Kobaratant Tablet 160/12.5 mg

Adult dose

The recommended adult dosage is 1 tablet of Valsartan 80 mg / Hydrochlorothiazide 12.5 mg once daily, to be taken with a small amount of water regardless of meals. For Valsartan 160 mg / Hydrochlorothiazide 12.5 mg, this applies only if prescribed. For patients with renal impairment, mild to moderate renal impairment does not require dosage adjustment. For patients with hepatic impairment, mild to moderate hepatic impairment without cholestasis should not exceed a daily dose of 80 mg of Valsartan.

This medication can cause serious harm to the fetus and newborn, especially during pregnancy, so it should be discontinued immediately if pregnancy is confirmed. People allergic to the components of this medication or sulfonamide drugs should not take it. It is contraindicated in patients with severely impaired liver or kidney function and certain liver diseases. Patients with electrolyte imbalances such as hypokalemia, hyponatremia, or hypercalcemia, as well as those suffering from certain endocrine disorders, should use it with caution. This medication may increase the risk of skin cancer, so sun exposure should be avoided, and skin condition should be regularly monitored. Dizziness or drowsiness may occur during treatment, so caution is needed when driving or operating machinery. Potassium supplements or potassium-containing medications should not be taken together without consulting a doctor, and blood potassium levels should be regularly monitored. Patients with renal or hepatic dysfunction should take the medication according to regular check-ups and medical advice. This medication may interact with other antihypertensives, diuretics, non-steroidal anti-inflammatory drugs (NSAIDs), so it's necessary to inform healthcare professionals about any drug use. In case of overdose, symptoms such as hypotension, arrhythmias, and electrolyte abnormalities may occur, requiring immediate medical treatment. Keep out of reach of children and store in a cool, dry place. Women who are pregnant or planning to become pregnant, and breastfeeding women should avoid taking this medication and consult healthcare professionals if necessary.

Serious side effects

Hives, severe swelling (including angioedema and edema), chest tightness, difficulty breathing, anaphylactic-like symptoms, angioedema, hepatitis, renal failure, hyperkalemia, hyponatremia, shock, loss of consciousness, agranulocytosis, leukopenia, thrombocytopenia, aplastic anemia, hemolytic anemia, necrotizing vasculitis, toxic epidermal necrolysis (Lyell syndrome), interstitial pneumonia, pulmonary edema, exacerbation of systemic lupus erythematosus, hypoglycemia, rhabdomyolysis

Mild side effects

• Headache
• dizziness
• rhinitis
• fatigue
• low back pain
• cough
• upper respiratory infection
• diarrhea
• joint pain
• abdominal pain

This medication is sensitive to air and moisture, so it should be stored in a tightly closed container. Also, it should be kept in a cool place below 30 degrees Celsius to maintain its effectiveness.

Appearance

Dark red oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle